Chapter 499: The Dawn of Victory
Hughes Medical Institute.
Led by world-renowned immunologists such as Qiu Xiang and Judson, everyone is waiting for the medication in the isolation room.
Now that the Reidman virus epidemic is serious and the situation is special, WHO and national centers for disease control and prevention have issued a notice that medical teams studying Riedman's specific drug can seek the consent of the families of awake patients to directly use tested non-toxic and minimally toxic drugs for patients who have lost consciousness.
This notification is very important because it eliminates the need for them to test new drugs on animals, which can greatly shorten the drug development cycle.
Now all of their drugs are administered directly to patients who have lost their minds. If they are not treated, they will definitely die, let them be treated with new drugs, and there is still a chance of recovery.
This is the 32nd attempt, and all members are praying for it to pass. They were divided into eight groups and worked on drug discovery research in nine different directions, and until now, there has not been much progress.
The Reedman virus is too domineering.
During the onset of the disease, the patient's other physical functions are much stronger than those of a healthy person, except for mental hallucinations. Half a month later, the patient will have internal bleeding and finally die.
Other than the modified HX3 potion, no other method has been found for the time being.
And the improved HX3 agent continues to be studied in depth, and they are also doing it, and after a month, it is simply no longer possible to suppress the virus.
After seeing the doctors in the isolation room injecting new drugs into patients, the hearts of all the researchers lifted. Ten minutes passed, and everyone showed disappointment when they saw the patient who was still struggling with fear and talking nonsense in the bed of the isolation room.
"Failed again."
Another failure made all medical scientists gloomy. Several old medical scientists, whose eyes were already red, felt their powerlessness in the face of such a disaster.
"According to incomplete statistics from the WHO, the number of direct and indirect deaths caused by the 'Grim Reaper virus' has exceeded 50,000, the number of infected and confirmed cases has exceeded 90,000, and the number of people in global quarantine is close to 2.5 million. In the next month, the death toll is expected to exceed 100,000 without a cure. This is the largest man-made biological disaster in human history. ”
"Los Angeles reported that yesterday, a medical worker in Los Angeles, while handling a corpse, accidentally contracted the 'Grim Reaper virus' and committed suicide by jumping off a building in the quarantine area due to excessive stress."
Reuters reported that in France's centralized quarantine area, a patient broke free from a fixed rope, killed a medical staff to escape from the isolation room, and released 60 people infected with the virus, causing riots in the quarantine area and attempting to escape the quarantine area.
As a result of the riots, three medical staff were killed, seven medical staff and one soldier were infected with the Reaper virus, and nine infected people died. The French military's anti-chemical warfare unit has arrested all the patients, and no infected people have fled the quarantine area. ”
In the past two months, the news from the hardest-hit areas in the world has made the hearts of the international community weigh on a big scale, and they must be cautious when they go out to do any activities, for fear of being contaminated with the 'Grim Reaper virus' and the global economic losses are immeasurable.
Capital Tangshan Hospital.
Chen Mo and Wu Bing, as well as a group of team members wearing protective clothing, were walking briskly towards the isolation room in the test area.
The expressions on everyone's faces were different, either anxious or expectant, but Chen Mo and Wu Bing's expressions were relatively calm. They are conducting a study and have been notified that the patient they received the trial vaccine had an abnormal reaction today.
With the support of Chen Mo's complete technical data and the help of team members, the research and development of vaccines is developing in the direction expected by Chen Mo, and the accuracy is very fast.
Wu Bing's team successfully found the protective antigen gene of the virus, and Chen Mo led the team members to find a suitable mRNA as a vaccine system platform.
The drug has been tried several times, all of which have failed, and the vaccine system platform has been re-refined several times, and this is the 8th trial of their customized vaccine.
It's a good thing to have a reaction.
At this time, the most terrible thing is that the drug does not respond.
So after receiving the news, everyone gave up their research and rushed to the test area.
"It hurts."
"It hurts."
"Doctor, I'm in so much pain, so uncomfortable."
When Chen Mo and Wu Bing entered the isolation room, they heard the patient's painful voice. The voice was not loud, but to the two of them, it was like heaven.
When the Reedman virus is sick, the patient is like a madman and does not have this clear voice at all.
This shows that their vaccine has begun to have a little effect.
"Sir, where are you uncomfortable?" Wu Bing leaned down and asked.
"My body hurts, and my brain hurts." The patient seemed to hear Wu Bing's question and began to answer, as if talking in a dream, but with a crying tone in his voice, obviously suffering a great deal of pain.
This answer made all the group members ecstatic.
There are answers, indicating that the patient's consciousness has been somewhat awake, and the vaccine may have taken effect.
Wu Bing asked a few more questions, but except for the pain, there were no accurate answers to the other questions, like a drunk who was half-asleep and half-awake.
"A full body check-up, you give him a blood test."
Chen Mo motioned to the team members who came over and began to draw blood for testing on the patient on the fixed bed. The other two team members untied the patient's hospital gown, and the bruise on the skin immediately attracted everyone's attention.
This bruise is found on all the skin of the body.
This is not a symptom of the Reedman virus, and they have been dealing with the virus for months, that's for sure.
"It's like allergies, it's like poisoning." Wu Bing said.
Chen Mo nodded and agreed with Wu Bing's statement: "In addition to the injection tube vaccine, has the patient used any other drugs?" ”
"No, the glucose injected by the patient, I strictly check. No other health care workers have been in contact with the patient. The member of the guard must have shaken his head.
"Maybe it's related to the vaccine, but we test the patient's blood first." Wu Bing said.
Twenty minutes later, with no results, Chen Mo and Wu Bing came out of the isolation room. As soon as the two came out, Shi Hongtu and the others outside the isolation room couldn't wait to surround them.
When they heard that Chen Mo's patient here had an abnormal reaction, they immediately put down the research in their hands. It's just that Chen Mo and Wu Bing are in the isolation room, they can't go in, and they are waiting outside.
"How? Is your research progressing? ”
Shi Hongtu and several other immunology experts looked forward to it under their protective glasses.
Chen Mo and Wu Bing's group, because of the research on customized vaccines, he has little hope. But after a few times, the group has progressed faster than he imagined.
Now the patient has responded, and the other groups, after injecting the new drug, either sink into the sea, or the patient dies directly, and the progress is not great, so they also hope that Chen Mo can create a miracle.
"The vaccine was injected three days ago, and depending on the situation, it should have played a little role, and the patient's no longer babbled like before." Wu Bing said.
As soon as these words came out, Shi Hongtu and several other immunology experts were ecstatic.
If the patient's mental state improves, it means that the research has progressed, and this is definitely the news they want to hear the most.
"However, the patient's body is abnormal, and he is not sure whether it is allergy or poisoning, and he needs to see the results of blood tests." Wu Bing added.
"Okay, okay, let's wait for the blood test results." Shi Hongtu said with some surprise.
Chen Mo and Wu Bing said goodbye to Shi Hongtu and the others and also entered the laboratory.
The team leaders of the other groups learned that Chen Mo's group had made progress, and they had no intention of researching, so they came over to wait with a few people. The waiting time is always very long, more than two hours, making several people feel like months have passed.
And when a few people were about to sit still, Wu Bing and Chen Mo came out of the laboratory.
Shi Hongtu's three steps turned into two steps, and he immediately walked up.
"The results are in?"
"Come on." Wu Bing looked at Chen Mo, and his voice couldn't tell the joy or sorrow.
"Antibodies to the virus are detected in the patient's blood, and these antibodies have an effect on the virus and can clear the virus."
Chen Mo's words were like a heavenly fairy song, which made everyone on the field ecstatic. Shi Hongtu was even more excited that the wrinkles on his old face were trembling, and he almost didn't cry.
"But the vaccine didn't work out."
This sentence made everyone's joy disappear, and they all looked at Chen Mo, waiting for his explanation.
"We detected two toxic proteins in the patient's blood. It should be a potential virulent protein gene that is present in the mRNA of the vaccine platform system. If this problem is not solved, the toxic protein accumulates in the patient's body until a certain concentration occurs, and the patient dies. ”
"What's next?" Shi Hongtu asked.
"Next, we need to find these two virol genes in the mRNA of the vaccine system platform, and find a way to replace these two virinoprotein genes to relieve the toxicity of the vaccine, so that the vaccine can be considered successful."
"Okay, I'll apply to the above right away, and call a few more genetic engineering experts to come over and help you find the poison protein gene." Shi Hongtu spoke without hesitation, his voice extremely excited.
As long as these two toxic proteins are found, and the vaccine is successfully de-virologized, they may be able to put an end to this global bioterror once and for all.
They have seen the dawn of victory.