At the Capital Institute of Biological Genetics, Wang Haoyi looked at the news about the Reedman virus in his experimental office, and thought from time to time.

This human catastrophe has been going on for several months, and the hard-hit areas have become unimaginably severe.

Unfortunately, his research field is to establish and optimize gene editing technology in hematopoietic stem cells and T cells, study the characteristics of related gene editing technology, and improve the efficiency and specificity of genes, mainly targeting genetic diseases.

This time the Reedman virus belongs to virology, and it is not so serious in China, and they do not need to be involved in approaching.

The virus has caused panic in the international community, but there is nothing he can do.

After reading the news, Wang Haoyi put down the newspaper and sighed. Worrying about other things is useless, doing your own research is the right topic.

Bang bang!!

Wang Haoyi was just about to start researching his subject when an old man with glasses knocked on the door and walked quickly in front of him, looking like he had something urgent.

"Director Liu, is there anything urgent?"

"Academician Wang, the dean is here to inform you that a breakthrough has been made in the Reedman virus vaccine in Tangshan, and urgent technical research is now being carried out, and genomics experts are needed now."

Hearing this notice, Wang Haoyi stood up: "I'll go over." ”

Without waiting for Director Liu to speak again, Wang Haoyi had already begun to pack his things and prepare to leave the office.

……

Tokai Institute of Life Sciences.

Yang Yunjia walked quickly into the laboratory, where there were members of their team, as well as students and assistants.

The key R&D plan of their team is precision medicine research projects, epigenomics detection technology and clinical application, as well as new technologies for RNA methylation epitranscriptomics sequencing, both of which he presided over.

The Reedman virus, which is hot outside, belongs to immunology, but he is not an expert in immunology and virology, so he was not summoned by the medical team and continued to preside over their research at the research institute.

But just today, the capital came to inform that the Reedman virus vaccine in Tangshan has made progress, and experts from genomics experts are needed to participate in urgent technical research.

"Teacher Yang, has something happened?" Standing in the lab, the other members and students looked at him, and one student asked.

"The capital needs gene editing and genomics manpower to carry out urgent technical research, Yu Jun, Mi Shuangli, you two come with me."

"Teacher Yang, is it convenient to say what kind of technology it is?" A female researcher named Mi Shuangli asked.

"From the Tangshan Hospital in the capital, analyze the genes of the Reedman virus vaccine."

"Okay."

The two nodded heavily and agreed without hesitation.

The Center for Disease Control and Prevention issued a convening notice, and experts and academicians in genomics and bioinformatics, who are presiding over research projects across the country, did not hesitate to agree to go to the Capital Tangshan Hospital to tackle key problems in the project.

In just one day, nearly 20 experts and researchers in genomics have arrived in Tangshan.

Personnel from the CDC and the Ministry of Health were aware of the importance of the project, and coordinated in the middle to quickly mobilize experimental equipment and materials to prepare the experimental conditions for the researchers.

Yuyama Research Institute.

Chen Mo and Wu Bing, as well as the group members, entered the conference room.

Seeing a room full of people, several group members were shocked. Some of them have already been recognized, including the existing expert academicians of gene immunology in the medical team, there are a total of 33 people on the field, almost including the top group of genomics experts and academicians in China, including their former mentors.

It can be said that the most influential people in genomics in China are in this conference room.

They were looking at the crowd, and so were the experts below. Seeing Chen Mo and Wu Bing leading, as well as the overly young team behind them, many people couldn't help but marvel.

It was this young team that made a lot of achievements in two bio-horrors, and this time it was also a breakthrough when they were not optimistic. Seeing that among the members of the group, there were their own students, some academicians smiled with satisfaction, at least their students were promising, and they were also very proud.

However, compared with Chen Mo, who took the lead, it seemed that any genius had become dim, and everyone's eyes quickly fell on Chen Mo.

In the past, I only heard his name and did not see his person, but today I finally see it.

Chen Mo is also an expert and researcher on the field of scanning.

The group could also find the poison protein themselves, but in order to speed it up, more people, obviously the faster. This time, the CDC and the Ministry of Health coordinated in the middle, and the two hospitals supported it, to find so many researchers, which was beyond his expectations.

After distributing all the materials, Chen Mo walked to the podium of the conference room and went directly to the topic.

"This morning, we did another blood test on the patient, and in your hands, there are test results. The patient has regained initial consciousness, the antibody concentration in his body has increased compared to two days ago, and the number of viruses is decreasing. Theoretically, in another five days or so, the patient will be able to develop resistance to the Reedman virus. ”

After Chen Mo spoke, everyone listened carefully to Chen Mo's explanation, many people on the field were old enough to be Chen Mo's teacher, but the level that Chen Mo showed was enough to be their teacher. The Reedman virus vaccine made a breakthrough under his auspices, and no one dared to despise Chen Mo because of his age.

Hearing that the vaccine was effective, many people were still a little happy, but they were just a little surprised when they were interrupted by Chen Mo.

"But we detected two toxic proteins in the patient's body, and these two toxic proteins also increased as the concentration of antibodies increased. Just two hours ago, the patient died in agony, less than five days later. He was not killed by the Reedman virus, but by the toxic proteins in his body that caused his death.

We preliminarily judged that this toxic protein was caused by the potential toxic protein gene in the mRNA of the vaccine platform system. So next, your task is to find these two toxic protein genes in the vaccine, and we will find a way to knock out these two genes and remove the toxicity of the vaccine. ”

"Academician Chen, is there any drug to degrade these two toxic proteins to achieve the purpose of treatment."

Hearing the interrupted question, Chen Mo nodded and replied: "We have thought about this method, the medical team is looking for drugs to degrade toxic proteins, but they have not found it so far, and it is not a cure for the symptoms. ”

"Academician Chen, a sample of toxic protein?" Yang Yunjia, who was sitting in the first row, opened his mouth to ask.

"Yes, we have some samples isolated from the patient's blood, but not many. Once the project starts, samples of the poison protein will be distributed to various laboratories. Next, I will explain to you the relevant characteristics of toxic proteins and mRNA. If you have any questions, you can interrupt and ask me or Academician Wu, and we will try our best to answer them if conditions permit. ”

After the explanation, Chen Mo began to talk about some characteristics of toxic proteins, as well as information related to mRNA, so that they could start researching.