"My hometown is Qingcheng County, Lianhai City, and a few years ago I went to work in Dr. Palama, the capital of Suriname, South America, and later met my husband and opened a supermarket, which is not large-scale, and hired a few local staff.

Two days ago, I suddenly received the news that my father was seriously ill, and after discussing it with my husband, I decided that I would go back to China to visit alone.

I first took a plane from Parimabo to the Netherlands for a connecting flight, arrived at Amsterdam Airport in the Netherlands at about 1 pm the day before yesterday, and waited at the airport for 9 hours.

I continued to wait at the airport because I was so hungry that I bought sushi at a small shop at the airport, and I ate it all.

Later, when it was time to board, I got on a flight from the Netherlands to Lianhai, and I felt itchy all over my body as soon as I got on the plane.

I went to the bathroom of the plane to check, and found that there was redness everywhere on my body, and there was a rash, and the more I scratched, the more I scratched, I thought I was allergic, thinking about what I ate before the plane, the only suspicious thing was sushi at the airport, but I am not usually allergic to sashimi.

As I flew on the plane, I thought that some of my colleagues who worked at the supermarket in Paramaribo had similar symptoms to me, and they went to the local hospital for a check-up, and the doctor said it was Zika fever, so I suspected that I had Zika fever as well.

After arriving at Lianhai Binhai International Airport at around 6 p.m. the night before yesterday, I took a bus directly to Qingcheng County People's Hospital, where my father was hospitalized.

That night, I had more and more red spots on my body, and I felt tired and uncomfortable.

I was worried that I was really infected with Zika fever, so I hung up an expert number at Qingcheng County Hospital early in the morning of the second day, but the doctor said that I was just atopic dermatitis and prescribed me chlorpheniramine, calamine lotion and Aoneng ointment.

I told the doctor that I had come back from the city of Paramaribo, which is a Zika fever endemic area, but the doctor said that he had never heard of Zika fever, and then after thinking about it, he said that there were no cases of Zika fever in the country, and that I did not have fever and did not meet the signs of viral disease.

But he also said that if I was really not at ease, I would go to the big hospital for examination, so I came to the best hospital in Lianhai City, and the infectious disease department of our First People's Hospital was called Dr. Gu. ”

Guan Peipei told his experience in detail.

Gu Yanan has read the relevant literature and knows that the clinical symptoms of Zika fever patients prevalent in South America are generally divided into two categories: one starts with fever, rash appears after 1~2 days, and the symptoms are more severe and need to be treated by medical treatment; The other type begins with a rash and can be cured with milder symptoms.

Guan Peipei's case should fall into the second case.

Gu Yanan asked, "Have you ever been bitten by mosquitoes since you returned to China?" ”

"Probably not." Guan Peipei replied in an uncertain tone this time.

"Are you sure? This is very important for our disease control and flow control. ”

Guan Peipei shook his head and said in a sure tone, "I haven't been bitten by mosquitoes, because when I lived in Paramaribo, there were many woods and flowers around our house and supermarket, and there were a lot of mosquitoes, and it was a Zika fever epidemic area, so I usually developed the habit of spraying mosquito repellent toilet water."

As soon as I got off the plane back this time, I sprayed toilet water containing 5% DEET, and I was not bitten by mosquitoes on the road, nor did I have a bag that had been bitten by mosquitoes recently, and the two bags on my legs were bitten by mosquitoes when I was in Paramaribo.

If I had been bitten by a mosquito, I would have been left with a painful and itchy red envelope, which was different from these red rashes on my body, so I was sure that I had not been bitten by mosquitoes after getting off the plane in Lianhai City. ”

Guan Peipei said with certainty, Gu Yanan breathed a sigh of relief in his heart, at least judging from the current flow survey results, although Guan Peipei may be the first imported Zika case in Lianhai City, the possibility of Zika virus spreading to the environment in her body is very low.

Although unlikely, mosquito eradication is a top priority to prevent the formation of natural foci of Zika virus.

Gu Yanan also asked Guan Peipei's specific address of the ward where his sick father was, as well as the people he had come into contact with and the places he had stayed in since he returned to China.

Coming out of Guan Peipei's ward, Gu Yanan discussed Guan Peipei's condition with Gu Jiashu.

Gu Jiashu: "There is no specific drug for Zika virus, and it can only be treated according to general viral infection, but Guan Peipei is in the early stage of pregnancy, and the medication needs to be very cautious, what do you plan to do next?" ”

Gu Yanan: "First wait for the test results of the laboratory, I still have to ask for a mosquito map with the Qingcheng County Disease Control." ”

"Mosquito map?" Gu Jiashu didn't react for a while.

"The Breto index, an indicator of mosquito density in a place. Recently, various counties and districts have been making mosquito maps, and I asked Qingcheng County for a copy of it, hoping to be below the safe value. ”

"Dealing with one of the four pests of mosquitoes is still your disease control practice, and when you have Guan Peipei's test results, tell me in time, the little nurses in the department are very worried." As Gu Jiashu spoke, a few little nurses passed by, and they listened to the news with their ears pricked up.

Gu Yanan realized that although the Zika virus does not have a big impact on ordinary people, it is a great harm to women of childbearing age and pregnant women, in case pregnant women are infected and give birth to microcephaly, it is a lifelong thing, affecting the next generation, so everyone is very concerned about this epidemic.

Gu Yanan glanced at the time on his wrist, "Two hours have passed since the specimen was sent to the CDC laboratory, and the results will be available in another hour, don't worry, I'll call you as soon as it comes out." ”

Gu Yanan and Xiao Chu returned to the CDC, and in the center compound, Gu Yanan instructed Xiao Chu to let him go back to the emergency office and call the mosquito map that Qingcheng County CDC had already made, especially the Breto index near Qingcheng County Hospital.

Xiao Chu promised and trotted away.

Gu Yanan did not go back to the emergency office, but went directly to the experimental building.

The office of Section Chief Li of the Laboratory Department.

Gu Yanan asked Section Chief Li about the progress of the experiment.

Section Chief Li: "I used the Zika virus nucleic acid detection kit issued by the national disease control and prevention, it has been on the machine for an hour, and the results will be available in more than half an hour, I just went to see the computer, the fluorescence signal value has begun to jump, it should be positive, but to be sure, we have to wait for the end of the fluorescence quantitative RT-PCR process." ”

The two went to the PCR room and waited for the final results.

Now that the fluorescence signal has begun to jump, the specimen can basically be determined to be positive, and the next action should be considered.

The detection of positive specimens should not only be limited to confirming that the Zika virus is positive, but also isolate the virus inside, isolate the strain, and then perform genetic sequencing, sequence analysis, and determine the source of the virus at the molecular level.

This process is more cumbersome, especially the step of isolating the strain, which requires a P3 laboratory and the need to raise cells, which takes at least three days, or even longer.

Gu Yanan suddenly remembered the nanopore sequencer that Li Yiming, the chief scientist of Nanmu Group's Baocheng Biological Company, had come to sell, and if there was such a sequencer, it would only take seven hours to get the full genetic sequence of Zika virus in the specimen.