Lianhai First People's Hospital, Department of Infectious Diseases, Isolation Ward.

Wang Peng, a suspected cholera patient, lies on a bed in an isolation ward.

Wang Peng's wife asked doctor Gu Jiashu about her husband's condition in the corridor outside the isolation ward.

Wang Peng's wife looked anxious, "Doctor, is my husband really cholera?" ”

"Now it's just a suspicion, and the diagnosis has to wait for the laboratory results."

There was a hint of panic in Wang Peng's wife's anxious face, "Doctor, my son and old woman also have a fever, could it be cholera?" ”

"Do they have diarrhea?"

"Yesterday there was no diarrhea, just a fever and it felt like a cold."

"I haven't seen the patient, and it's hard to be sure now, you'd better let your son and mother-in-law also come to the hospital for a check-up, and the CDC people will be there soon, you will report the situation to them later, and the CDC people have experience and will do the investigation."

As he spoke, Gu Yanan had already arrived at the Infection Department with the sampling box.

"Brother, how is the patient?" Gu Yanan asked bluntly.

"I was rehydrated and rehydrated, and antibiotics were used, but the condition has not been controlled, and the hospital laboratory department is doing a test for Vibrio cholerae, and the results will be available after a while."

"Do you have a patient's medical record?"

"Yes, it's right at my hand, and I know you're going to come and prepare it in advance."

Gu Jiashu handed the case file in his hand to Gu Yanan.

Gu Yanan began to look through it, Gu Jiashu explained on the side: "This Wang Peng lives in Beicheng District, Lianhai City, is a white-collar worker, usually works in a company in the commercial center of Beicheng District, lives in an old-fashioned residential building in Beicheng District, usually interpersonal communication is very simple, colleagues and family members, recently had diarrhea symptoms, last night also went to a restaurant with colleagues for dinner, after returning home, the symptoms worsened in the middle of the night, fainted after diarrhea many times, was sent to the hospital by his wife, the emergency department was preliminarily diagnosed as dehydration shock, the patient woke up after rehydration and rehydration, However, the white blood cell count in the blood picture is very high, there is an infection, and antibiotics have been used but the infection is not controlled. ”

Gu Yanan thought to himself, judging from the medical records alone, this Wang Peng is indeed likely to be infected with cholera, but to confirm the diagnosis, it is necessary to look at the patient's symptoms and laboratory test results to be sure.

"I'm going to see the patient first." Gu Yanan demanded.

"Okay, follow me."

Wang Peng's wife stopped the two and demanded, "I also want to go in and see my husband." ”

Gu Jiashu hesitated for a moment, but finally nodded in agreement, "Yes, but you have to wear protective clothing with us." ”

In the isolation ward of the infection department, Wang Peng's wife, Gu Yanan and Gu Jiashu stood beside Wang Peng's bed in isolation gowns.

Wang Peng's eye sockets are deep-set, obvious symptoms of dehydration, and antibiotic needles are hanging on his arms, although he is very haggard, but his consciousness is very clear.

Wang Peng ignored the doctor, but asked his wife directly, "How is Feifei?" The doctor said that I might be cholera, this disease is very contagious, Feifei and my mother should not be infected by me, you should bring them to the hospital for examination. ”

The wife comforted her husband, "The doctor has already told me, and when you are dealt with, I will take them to the hospital immediately." ”

Wang Peng was not satisfied with his wife's answer, and urged: "What is there to deal with here, there is a doctor here, and you can't help, you should go back quickly and bring Feifei and my mother to the hospital." ”

Wang Peng's wife was a little resigned to her husband's request and was ready to leave the isolation ward and go home.

Gu Yanan had already heard the general idea from the conversation between the two, and called Wang Peng's wife, "Wait a minute, I will ask my colleague to send you back and collect specimens around your house by the way." ”

Gu Yanan immediately called the emergency office and asked Zhou Jie and Gao Fei to drive the on-site flow shunting car to pick up Wang Peng's wife at the People's Hospital first, and then go to Wang Peng's house with her.

After Wang Peng's wife left, Gu Yanan began to ask Wang Peng about some information.

"When did you start experiencing diarrhea?"

Wang Peng thought for a while and replied: "In the past month, sometimes it has been good and sometimes bad, and I didn't take it seriously, until last night, when the symptoms suddenly worsened." ”

Gu Yanan's brows wrinkled slightly, judging from Gu Jiashu's description and the patient's symptoms before, it was very likely to be cholera, but the patient now clearly said that his diarrhea symptoms have been more than a month, which is not quite consistent with cholera, but it is not ruled out that it was a hidden cholera infection before, maybe Wang Peng has a cholera source of infection around him, he is often exposed to Vibrio cholerae, so he will have symptoms of diarrhea that have not been too serious, and yesterday he was exposed to a large number of sources of infection, so he will have very typical cholera symptoms.

Based on the inference he had just made, Gu Yanan asked, "The name and location of the company you work for?" Where did you and your colleagues have dinner last night? And who are the colleagues who attended the dinner? I need detailed locations and names of people. ”

Wang Peng elaborated one by one.

After Gu Yanan asked Wang Peng about the news she wanted to know, she took a sample of Wang Peng and left the isolation ward.

On the way back to the CDC laboratory with the samples, Gu Yanan began to assign tasks on the phone.

Previously, Zhou Jie and Gao Fei were sent to Wang Peng's house for investigation, and now Lu Li and Wang Xiaoxiao were sent to Wang Peng's company and the restaurant where they had dinner last night.

Lu Li found a colleague who attended the party last night in Wang Peng's company, and found that except for Wang Peng, everyone who attended last night's dinner had no diarrhea symptoms, but Lu Li still routinely collected blood from everyone and collected fecal samples.

Wang Xiaoxiao found the restaurant where Wang Peng and his colleagues had dinner last night, took food samples from the restaurant, and took blood samples from the hotel staff, including waiters and cooks.

Gu Yanan returned to the CDC laboratory with a sample from patient Wang Peng to detect the virulence gene of Vibrio cholerae using the fastest PCR method.

Two hours later, the results of all the specimens came out.

Vibrio cholerae virulence gene negative.

Under the microscope, the fecal specimen of the patient Wang Peng was not tested, and no fish-like Vibrio cholerae was found.

At the same time, the test results of the hospital's laboratory department also came out, and no cholera-related pathogens were detected.

No cholera pathogens were detected, and Wang Peng ruled out cholera.

If he is not infected with cholera, what is the reason for Wang Peng's current symptoms?

——

Wang Peng's home.

Zhou Jie and Gao Fei arrived with Wang Peng's wife.

In the house, Wang Peng's son and mother both had high fevers, and Wang Peng's mother also had severe diarrhea symptoms since the morning.

Before Zhou Jie and Gao Fei began to take environmental samples of Wang Peng's home, they called 120 to prepare to send Wang Peng's mother and son to the People's Hospital.

After that, the two began sampling.

Wang Peng's home is very neatly furnished, the home is well maintained, and the living room can be described as "spotless".

The kitchen is the same, everything in the refrigerator is sealed with plastic film, neatly arranged according to the category, and there is no greasy appearance on the stove.

Zhou Jie opened the refrigerator to sample the food, and at the same time sighed to Wang Peng's wife, "Your home is really clean, if only the one in my house had half of your love for cleanliness." ”

Wang Peng's wife's face was slightly embarrassed, "Actually, it's because my husband has a habit of cleanliness, so I have to do this." ”