Chapter 180: How Blood Is Made
Zhou Yunsheng saw that after they finished speaking, she said directly: "I don't understand what you said, let's go and see how the blood is made." ”
She looked at Du Xianyu again and asked, "Director Du, have we applied for the blood products we know to the Food and Drug Administration?" ”
"I informed Wang Tong that he sent someone to take the sample, saying that he wanted to apply to the Food and Drug Administration. I didn't ask in detail how long it would take for the results to come out. Du Xianyu replied simply.
"Oops, why didn't I get the message. According to the procedure set by our company, they have to escalate and I should be the first to receive the news. They don't notify me, and the CFDA's mobile app will notify me. Zhou Yunsheng said strangely.
At the same time, she took out her mobile phone and clicked on the cloud intelligence platform. After reading it, he said with relief: "It turns out that they are applying and have not yet been officially approved." This product is no longer on the priority list and needs to be queued. ”
After Zhou Yunsheng finished speaking, they wanted to go to the place where blood and its blood products were made.
It can be seen from Du Xianyu's words that now the blood manufacturing technology is mature and can be industrialized at any time.
Under the leadership of Du Xianyu, they walked along the glass corridor of the biological laboratory. Walk to the laboratory responsible for making blood and blood products.
Li Hao saw that they were separated by a transparent glass wall, and they could easily see the scene in the laboratory.
There's nothing special about the lab, except that there are a lot of large glass tanks inside. Most of the liquid inside the jar is colorless and transparent. Only two large jars are the most special, one dark red and one pale yellow.
An experimenter who just wanted to enter the laboratory saw Du Xianyu and Li Hao standing here, and walked over to say hello to them.
The experimenter holds a glass box containing materials for slow experiments and wants to enter the lab.
He first went up to the glass room next to him to change into the protective suit he was wearing, and then a blue-purple light lit up on the roof of the glass room.
Zhou Yunsheng looked curious, and asked Du Xianyu: "Is this how they kill viruses?" ”
Du Xianyu introduced to her: "This is through high-intensity ultraviolet sterilization and electrostatic precipitation. Ensure that no contaminants enter the laboratory. ”
Zhou Yunsheng stared at the way blood was made in the laboratory. She pointed to the lab and said, "This seems very simple, and I see that they are not too complicated. ”
"It looks very simple, but the technology behind it is very complex. It took tens of thousands of experiments to find the best match.
Blood is no other substance, it transports the body needed for oxygen, nutrients and metabolizes out waste products.
A slight difference in the composition of each component can cause rejection of the organism. The strictest rejection reaction is to drain the blood immediately and replace it, but it cannot be stopped. The mouse died a few minutes later.
The core technology of our blood is the ratio of each component, which is more important than hematopoietic stem cells.
In particular, we should consider the preservation time of the blood, adding our special additives to preserve it as much as possible without affecting the efficacy of the blood.
Now we produce blood, it can be stored for about 60 days. ”
Li Hao saw the large jars densely packed in the laboratory. He also didn't quite understand the way blood is made, so he asked Director Du, "Director Du, can you briefly talk about how blood is made." ”
Du Xianyu pointed to the equipment in the laboratory and said: "We also use the principle of biomimicry, modeled after the production of blood in living organisms.
We started by harvesting highly active cells from living organisms. Using certain technical means, it is induced to differentiate into hematopoietic stem cell progenitor cells.
These progenitor cells are the cells that the embryo produces in about 10 days. It has a high degree of differentiation ability and can not only differentiate into blood-related cells.
It also has the function of differentiating into lymphocytes. It's just that the body's immune system is too complex, and it is a very delicate system, and a slight mistake has a great impact on the human body. We have not yet found the role of lymphocytes.
Hematopoietic stem cell progenitor cells are then differentiated into hematopoietic stem cells. Hematopoietic stem cells, under certain conditions, differentiate into red blood cells, white blood cells, platelets and other blood cells. ”
Du Xianyu pointed to the red glass jar and said: "This is the place where red blood cells are cultured, and the cells we culture are basically not much different from the cells in the human body. After animal experiments, it can play a role in transporting oxygen. ”
He pointed to the pale yellow culture tank and said, "This is plasma, and it has a pale yellow appearance because of the bilirubin in it." The configuration of plasma is the most difficult for us.
As long as the blood cells get the hematopoietic stem cells, the rest is a matter of course.
However, it is extremely difficult to prepare plasma, and each person's plasma composition is slightly different. We can only find the greatest common divisor to ensure that plasma will be safe and stable in anyone's body.
It is about 90% water, and there are some trace elements and a variety of proteins in it. When other substances are lacking in the human body, they will naturally be produced.
Plus there will be no one whose blood is all drained and who is still alive. So less of the substance will not have an effect on its effect.
Plasma and blood cells are mixed together in a certain proportion to form our artificial blood. ”
Du Xianyu sighed, and he continued: "Our artificial plasma can only replace two-thirds of the blood at most. It has many trace ingredients that we haven't studied thoroughly.
We experimented with mice, draining the whole body of blood and replacing the blood we made. After that, he was still able to live a normal life, but he seemed to be depressed and not lively at all.
After experiments with a variety of animals, we found that when artificial blood is replaced with 80% of the total blood, the organism will have side effects. ”
Zhou Yunsheng looked at this blood manufacturing laboratory, she had always had a question, and after hearing Du Xianyu finish speaking, she immediately asked: "Director Du, we have six blood types, and I see that there is only one blood type in this big jar." How to use it in patients with other blood types. ”
"There are 34 blood types in the human body, and we have arranged them in other labs. Hematopoietic stem cells are prepared for each blood type.
The main blood group tests are ABO and RH, but other blood types can also have adverse consequences for people.
From the very beginning of the manufacturing of this technology, we strive to be comprehensive, ensuring that each blood type can produce enough blood. ”
Zhou Yunsheng covered his mouth and said: "It turns out that there are 34 blood types in humans, and I always thought that there were only ABO and RH blood types. ”
After they visited the blood manufacturing laboratory, Li Hao and Du Xianyu separated. Du Xianyu went to continue to inspect the progress of each laboratory.
Zhou Yunsheng pulled Li Hao and ran to the medical team, she said that she was going to find an ophthalmologist, Dr. Qian Minghua, to help Zhou Yuanyuan ask about the eye transplant.
I also took Li Hao to find the old Chinese medicine doctor Li Deren, saying that Li Hao has been in poor health recently. It just so happens that the company has an old Chinese medicine doctor with superb medical skills, and he wants to recuperate for him.