Seeing that the secretary had already intended to leave, I went to the reception area to sit next to Jiang He, and Jiang He said to me: "You see that white building, you may have to stay there for a while in the next period." ”

"You were there before?" I asked.

Jiang He approached me and whispered, "If I'm not mistaken, the wards that may be used are all the same, and if you are lucky enough, you can still smell the breath I left there." ”

"Maybe you can even pick dog pee."

Jiang He poked me.

Li Ting smiled and said, "Why are you still the same as when you were a child." ”

The secretary left quickly, Jiang Feng came over and sat down with a smile, and said, "Wait a minute, Xiao Meng will come over to introduce the condition, and then we will study the treatment plan in detail." Before I do that, I'll give you an account of the situation and the heavy rain. ”

Jiang He and I glanced at each other, and I guess the so-called confession should be to talk about the experiment in Xinjiang.

"I think we Xiaohe should tell you all the stories, right? I won't repeat that part, maybe she has her own private goods in her narrative, and if I say it again now, I may get into a dispute, so if you have different opinions on many things, you can slowly investigate them later. ”

"Today we talk about the cause itself. I have been engaged in genetic research for 30 years, and many people do not know about this profession, thinking that it is a new discipline that has only recently emerged, but in fact, genetic research has a history of more than 150 years. It's just that the process of human understanding of genes is very slow, and it was not until the fifties of the twentieth century, with the development of molecular genetics, especially after Watson and Crick proposed the double helix structure of DNA, that people further understood the nature of genes, and I was born at that time. ”

"Genes have two characteristics, one is the ability to faithfully replicate themselves in order to maintain the basic characteristics of living beings; The second is that genes can mutate and mutate when reproducing offspring. Mutations generally produce genetic diseases, which is the bad side; There is no problem with the variation of life under normal genetic conditions, which is the source of diversity. ”

In order to decipher the full nucleotide sequence of human DNA molecules and establish a complete database of genetic information, the Human Genome Project initiated by the United States was launched in 1989, with the participation of six advanced countries, including China, and announced the completion of human genome sequencing in 2003. This is a tremendous achievement, and since then, more than 5,000 genetic diseases, as well as malignant tumors, cardiovascular diseases, and other diseases that seriously endanger humanity, have been prevented, diagnosed and treated at an early stage. ”

"In fact, a year before they started their project, in '88, your father and I had access to a complete human genome sequence. It was an unbelievable thing, so your father and I didn't take it seriously at first. ”

"Don't ask me where the information comes from, there's no comment on that. Your father and I spent a lot of effort sorting out the amount of information and encrypted data, so we found that the genome sequence is just the most basic thing, just a basic threshold within the scope of our understanding, and only when we understand this will we have the opportunity to verify the advancement of other data. The goal of this information is big, but there is not much work that your father and I need to expand on, and for the next three years, we will only replicate a few experiments as instructed. ”

"The ultimate goal of the experiment is not clear to us, it is like exploring a cave, we don't know what might be in the cave, and it is difficult to say whether it is a blessing or a curse to take a risk. At the same time, the progress of the work of scientists in the six countries continues to verify the correctness and advancement of this data, and the great curiosity makes us eager to know what the experiment can bring if it is carried out step by step. ”

"The engineer who made the atomic bomb said he didn't know what he was building, do you believe it?" Jiang He interjected.

"You should understand that the nature of biotechnology is much more uncertain than that, and I just emphasized that the advanced nature of that information is very advanced, at least beyond our judgment ability at that time." Jiang Feng paused for a moment and continued: "Before the human genome was sequenced, everyone thought that the complexity of human functions was achieved through more proteins, so it was expected that the number of human genes would be much larger than that of other organisms, but after the human genome was sequenced, it was found that human beings only had about 23,000 genes that could code for proteins, accounting for 1.5% of human DNA sequences, and the remaining 98.5% were non-coding sequences, which were once considered useless and junk DNA. It is only in recent years that this part of the DNA sequence has been found to be useful, and the vast majority of them are functional, and this part has a total of up to 4 million switches and functional regulators, which actually has greater research value. ”

You may not understand these words, but to put it simply, our scientists have only recently learned that in addition to the 23,000 genes that they believe have a coding function, most of the other DNA sequences that do not have a coding function are actually functional. And the information we got does not classify human DNA in this way, but records the respective functions of human DNA sequences in detail, which our scientists have not done until now. ”

"Isn't that outrageous, you and my father got a copy of the information in the eighties that surpassed the current level of biotechnology? Isn't this a science fiction story? I couldn't help but interject.

I have been persuading Jiang He not to lose his temper with his father, but at this moment the disgust in my heart has overflowed my reason. Although Jiang He's questioning of her own cause affected me somewhat before, I still felt that she was mostly angry and prejudiced because of love, and I didn't expect Jiang Feng to be so foolish at that time, so no matter how malicious the speculation was, it would become targeted.

"Your reaction is similar to that of Xiaohe back then, you think I'm talking nonsense and making up stories, but even if these are my words, I can't shirk my responsibility to you, why should I talk nonsense?" Jiang Feng still habitually spread his hands, Jiang He and I looked at each other for a while, and there was nothing to say for a while.

"There are multiple channels for the development of science and technology, especially some technologies that can be militarized, you can't expect to learn from online newspapers where the real academic frontier is, don't be presumptuous about things that are beyond the scope of your knowledge." Jiang Feng said with a smile, which made me embarrassed about my impulsiveness for a while.

"I was sick when I was young, and now I want to know, can your so-called information and trials be provided to be investigated and stand up to investigation?" Jiang He asked.

"When you want to investigate, I will cooperate within the scope of non-confidentiality." Jiang Feng looked at Jiang's mother and said, "Your mother has quarreled with me many times for unfounded suspicions, and it may be good for everyone to investigate." ”

Jiang Feng turned to me: "The reason why we stopped the research experiment after three years was also because of the advanced nature of the data, we began to become unable to understand and control the results of the experiment, so we had to stop in a hurry. It was many years later that I discovered that your father and I were genetically contaminated to varying degrees, and because the degree of contamination could not be confirmed, it was not certain whether it would be passed on to our children. Your father and I quarreled on the night of parting, also because I prudently informed him of this possibility, in order to help detect the problem as soon as possible in the future, but it also caused him to break off his friendship with me in a fit of rage. ”

"Isn't the IVF and twin thing unrelated to all of this?" Jiang's mother asked.

"I've explained many times that IVF is really a coincidence, and I really haven't discussed it with Anguo. We've been working together for over three years and fiddling with test-tube reagents all day, so it's very likely that we'll be influenced by the same philosophy and take the same steps when faced with the same problems. As for the twins, it has always been impossible to verify, and under normal circumstances, when there is a small probability result repeated in the test, the test method and test materials are generally tested first, so there is a high possibility that the test reagent will have problems at that time. Jiang Feng's attitude was very sincere.

I saw that Jiang's mother stopped talking, and then asked, "What problems did your experiment cause at the beginning, and what kind of problems did you pass on to us?" ”

In fact, most of the non-coding DNA refers to DNA that cannot be directly translated into protein under the central law. The difference between higher organisms and lower organisms in non-coding DNA is much greater than that in genes, and the value of this part of the difference is very great. Our research focused so much on this that our experiments resulted in a portion of your and Jiang He's non-coding DNA sequences mutating into codeable genes, and as a result, the number of your genes was much higher than that of the average person, reaching more than 40,000. Under normal circumstances, even if the contaminated sperm is successfully conceived, it is impossible to produce offspring because the system is not self-consistent, but it is unbelievable that you are all born healthy. But after all, the fundamental problem still exists, the self-consistency of the system is very fragile, and it may collapse at a certain time, and after realizing this, I was inspired by that information and found a cure. ”

"That means you can turn off the genes that were illegally activated and return them to normal levels?" I asked.

"It's impossible to shut down again, encodeable DNA is the record of information, relying on this information to make people human, you have more genes, so the two of you get more genetic information than others, your physique is more similar to your parents, this heritability is irreversible, what I can do is to make the whole human body system recognize all genes as legitimate."

I didn't know what to ask for a while, I didn't understand Jiang Feng's words very well, and I had no idea what it meant to have a bunch of extra genes after being cured.

Jiang He understood my confusion and directly picked it out: "That is to say, after being cured, your genes are different from ordinary people, and the number of your genes is almost twice that of normal people, so your chromosomes are twice as complex as normal people." But this will not give you superpowers, you can't become Spider-Man and fly in the sky, your physical intelligence is no different from ordinary people, but your body is more hereditary from your parents. After being cured, you won't be able to die for a while, but you can't get married and have children like ordinary people in this life, and you're not the same as their genetic sequence, so it's hard to say what kind of monster you'll give birth to, that is, if you want to get married, you'd better get ligated by the way during this treatment. ”

Jiang Feng said: "This is maliciously misleading. ”