Chapter 22: Chimeras
Jiang He said: "If the pick-up man even cares about this, he deserves it, and he should bear moral pressure, after all, the exogenous effects are multifaceted, and the impact of eating a bowl of wontons on the street to infect hepatitis B is much greater than these." ”
Jiang He continued: "The purpose of saying this is actually to show that genes are very selfish, and it is completely self-interested. The fetus does not have any moral motive for doing this, they just want to improve the maternal environment so that their development is healthier. ”
I nodded: "People are really not good things, they can't give birth to anything, they know that they can suck milk and drink blood, and they can't live without their mother for three days. "The dim sum is delicious, and the scolding and eating of the food are all healing, and it can really make people forget about the troubles in front of them for a while.
Jiang He said: "This is not the point of what I said today, in fact, there is a more selfish situation, called fetal mosaicism." ”
I asked, "Two fetuses fused?" The kind where the two heads share a torso or the kind that shares a spine with their backs together? ”
"No, it's a malformed fetus, not one of them. In his book "The Selfish Gene", Dawkins argues that we are not the masters of this world, but that our genes are. He believes that every gene is seeking to replicate itself more, and the body is just a temporary gathering place for genes, a living container for genes, and genes do everything to survive in order to survive. ”
Jiang He continued: "The most selfish behavior of genes in the human world is undoubtedly fetal chimerism, which generally occurs between twins, in the way that one fetus absorbs the other, as for whether it kills the absorbed or absorbed stillbirth, this question is very uncomfortable to ask, so I won't say much." And this generally happens in fraternal twins, where the surviving fetus will have two sets of DNA, one from the original and one from its fraternal twin. The number of his genes naturally doubled, and the two cells differentiated into the same body. ”
"I see what you mean." I put down the snack in my hand and became serious: "Can this kind of person grow up healthily?" Is there a problem that the system is not self-consistent? ”
"Normal childbirth generally has no health problems, in fact there is basically one such person in every 1,000 people, but they are only detected in very special circumstances. For example, during the paternity test, it was found that the child was not his own, but belonged to an immediate relative, and an in-depth examination found that the genes of different parts of his body were different, and he was a chimera of two people. This is the real Chimera, a mythical beast among humans. ”
"You're not making it up, are you?"
Jiang He glared at me: "I am a master's degree in anthropology, and I still have at least academic literacy, and this is not cutting-edge and cold knowledge, you can find relevant information." ”
I said, "This situation is still very different from ours, they are naturally generated, although the genes of different parts are different, but the number of genes in the same part is normal, and there is no hindrance; And we are not, there is no difference in our genes, the number of genes as a whole has doubled, and the body does not recognize it. ”
Jiang He paused and said, "I know this, my focus is on the suspected twin problem back then." I'm inclined to suspect that my dad doubled the number of genes through the idea of twin chimerism, but of course they did it more complicated, and achieved the overall doubling of genes through preliminary experiments, rather than simple chimerism. In the past few years, I have looked through a lot of information, and there is no evidence that the nature of human DNA can be transformed, and it is completely impossible to increase the number of genes, and my father is fooling us. ”
I interrupted, "It's still a suspicion that they did a human experiment on purpose, and they went around in a circle like yesterday, why did our father do that?" It's irresponsible to the point of madness. ”
"That depends on the purpose, and if the benefits of that purpose are extremely tempting compared to the harm done, it's hard to say, at least I don't think my father has resisted the temptation."
I asked her, "This benefit is definitely not brought to us, what do you think it will be?" ”
"It's not necessarily, maybe at first we thought it would bring us some kind of benefit, but not only did it turn out, but there were also sequelae, maybe that's why they turned around on the last day. To fully understand, investigate the original purpose as well. ”
"Your dad can't check this if he doesn't cooperate."
"Not necessarily, you didn't listen carefully just now, fetal mosaicism basically occurs between fraternal twins, both of us are IVF done in the hospital, if you want to do fraternal twins, you must cooperate with the attending physician."
I couldn't help but praise her: "Your entry point is amazing, that is, you want to investigate the doctor at that time." ”
"So when you are cured, we will go to Xinjiang, generally IVF is to solve the problem of infertility, and there must be very few people who dare to propose to be fraternal twins."
However, I also have doubts: "But I think the doctor, even if he remembers, may have only helped with the twins as requested, and is unlikely to know anything else." ”
Jiang He said: "That's enough, as long as it is proved that it was a twin at the beginning, then everything today is intentional and purposeful." ”
I was so impressed that I asked Jiang He: "Is this kind of research exclusive?" Do you know that there are other applied studies on this chimera in the world at the moment? ”
Jiang He said: "Of course there is, and it is quite avant-garde, but the thinking is different, and what people study is the simple chimera of non-fusion. I've seen reports in Japan where Japanese scientists want to transfer chimeric embryos of pigs and humans into the uterus of pigs for development. They hope that as the animal matures, these human stem cells will be able to develop into fully functional human organs, such as human kidneys, livers, etc. This means that when the chimeric embryo develops into a full-fledged animal, scientists can obtain human organs from the animal and use them for organ transplantation. ”
I interrupted her: "I have to be cured tomorrow, this is disgusting, you might as well not tell me this." ”
Jiang He ignored me and continued: "Plugging human stem cells into pigs, and when the pigs grow up, they will have a pair of human livers and lungs, which are similar to Zhu Bajie, how good you say this is." Moreover, the genes are not infected with each other, and they can be transplanted after harvesting, as long as you pay attention to the fact that you must be classified when you put them in the refrigerator, don't accidentally fry the wine. So if my father wanted to study chimera at first, it would have worked in the technical direction, and it would have been too easy for him to follow, and he said that he was not bragging about winning a few Nobel Prizes. ”
"Can we stop this addiction? The two of us can't be some spare products that have been made, right? ”
"That's not all, our genes are fusion chimeras, different from ordinary people, and our organs can't be used by others. However, all possibilities should be considered, and more ideas should be explored. I told you yesterday that it's important to improve your ability to ask questions, you've already made progress, maybe I'll think of something else tomorrow and I'll share it with you when the time comes. ”
"If it's all disgusting, you'd better have it to yourself. I also admire the Japanese, who can turn your appetite at the end of everything they do. ”
"Didn't you just study Japanese women?"
"I just wanted to find out why the cover photos they took were so good, but the video showed that there were two of them, and why the Japanese always lost their appetites, and is there any anthropological explanation for this?"
We continued to chat in the tea pavilion, most of the time talking about childhood anecdotes, no longer talking about topics related to the disease, in fact, no matter how much we talked about it, it was all speculation, it was better to enjoy this hard-won good time. I ate a lot of snacks, so I wasn't hungry at lunchtime.
Later, I was sleepy and proposed to sleep for a while, so Jiang He and I each curled up on the Changchun bench and fell asleep. When I woke up, I saw a long leg, Jiang He crossed his feet to my side under the table, and his feet in black stockings were an inch away from my face.
I reached out and grabbed her foot, and when she dodged, her knee hit the table, and I was so angry that I said, "I deserve it, why is it that the bigger it is, the less dignified it is, I am neither a stocking control nor a beautiful leg control, don't want to corrupt the good youth." ”
"I've been sleeping for twenty minutes since I woke up, it's past three o'clock, isn't three hours of sleep enough?"
"Make tea."
"Do you know what I'm most afraid of in Japan?"
"Japanese men?"
"It's athlete's foot. Japan has an oceanic climate, and a quarter of the people have athlete's foot. They also like to take off their shoes, and they take them off everywhere. Needless to say, when I go home, I have to take it off when I go to restaurants and even some companies, and although I have a layer of socks, I am still afraid of infection all the time. ”
"It seems that you have a hard time in Japan."
"You don't understand, in fact, if I was allowed to choose freely, I would stay in China, and the best direction for going abroad is definitely not Japan."
I said, "Well, studying anthropology in Japan is not even a compared to the United Kingdom." I didn't want to go abroad, when I was a kid my dream was to go all the way to the west, and my dreams were all desert dunes. I often fantasize about sleeping through the Gobi Desert, finding the fountain of immortality in the legendary oasis, and then filling two pots and sharing them with friends and family. In particular, I want to give you two more sips to drink, and we can stay at ten forever. Later, when I grew up, I thought it would be good to stay at 20 years old. Today, it's okay to stay at any moment. ”
"When I was twenty years old, I was in Japan, who did you pour it back for? You actually gave my fountain of immortality to someone else to drink? ”
I ignored her and continued, "I don't know if you believe in fate, you know why I haven't been so excited about my illness these two days?" Because of the blessings and misfortunes, if it weren't for this disease, we might never meet again in our lives, we are on different sides of the world, and it seems that we have no ability to involve each other in our life plans. ”
"I believe that fate is cause and effect. I'm not so dazed compared to you. ”
"There is a cause and effect, but there may not be me."
Jiang He leaned over and stared into my eyes again.
I asked, "What do you see?" I've slept again, can I be sure I'm me now? ”
Jiang He laughed, as warm as the autumn afternoon sun.
On the way home, I asked Jiang He if he said he was going to buy diapers in the morning, Jiang He was silent for a while and couldn't help laughing, saying that it was just a joke.