"Sir, with all due respect, a normal cell does have the potential function to develop into a complete individual, but because in the process of cell differentiation, many genes are silent due to the inevitability of evolution and induction, and it is not too difficult to find out the genes that may be related to stem cell activity and further differentiation?" After everyone else was gone, Hurt, who was left behind, said to Junxin.

"You are engaged in the research of signaling pathways and related ones, and the topic itself is also just emerging, so there is really no document that can be used as a reference!" The underlying meaning of Hurt's words, Jun Xin could naturally hear it, and after Hurt finished speaking, Jun Xin shook his head and explained: "But these things are not traceless. You've been doing stem cell research for so long, and you've had a pretty high level of stem cell research, but in my opinion, haven't you thought about the mechanism of stem cells at the molecular level? ”

"Do you have any suggestions?" Hurt could hear the dry goods in Junxin's words, and couldn't help but say with a little respect in his heart.

"Dr. Hurt, all I need is a general range of genes, although we can't know all the sequences of a species, but we know the approximate genotypes, so I need you to try to screen out these genotypes that may act on stem cell differentiation, or maybe five stem cell related expression or regulatory genes, not need a definite answer, this should not be a problem, right?"

"Got it!" Hurt nodded, "Again, all I can say is that I try my best!" ”

"It doesn't matter, you can also tell me that you can be sure first, once Shashefsky's side is adjusted, we will first start to engage in the forward differentiation of stem cells to determine the changes in gene expression after induction, further confirm, and when it is determined, we will explore relevant inducible factors that can induce reverse differentiation." Junxin shook his head and said.

"Yes, sir!" Although Hurt was still a little confused, his thinking of this topic was indeed extraordinary, so he had no idea of continuing to ask. Anyway, when the time comes, I will take out what Junxin needs and continue to read it myself.

"Sir, then I'll go back first!" After Hurt took the notebook, he said hello to Junxin and walked in the direction of the library. In these days, there are no computers and databases, and there are no websites with similar gene sequences such as NCBI, so a lot of information needs to be searched and excerpted through abstracts and journal search tools, and it is indispensable to go to the library to find journal files.

"Sir, I have one more thing I want to ask!" When Junxin just walked out of the door of the laboratory, he was suddenly stopped. Junxin turned around and saw that it was Shirley Xavier.

"Oh, if there's anything I need to solve, let's talk about it now!" Junxin said patiently.

"It's still about my graduation thesis, in fact, both me and Michigan-Green are students of Professor Ivanov, I still have a year and a half to graduate with a Ph.D., and in the same way, Michigan has more than a year to graduate and is almost about to graduate, we need a supervisor to come over and take over our project as soon as possible, otherwise we are very likely to not be able to complete our studies and get our degree certificates!"

"So, dear Lady Xavier, what do you think about this matter, or do you have any intentional mentors?"

"Princeton has very few mentors in stem cell research, but many in the structure of biological macromolecules, which is why Professor Ivanov eventually left Princeton." Shirley Xavier did not directly mention her own suggestion, but gave Junxin a brief explanation of the actual biological situation of Princeton in her words.

"Professor Ivanov contacted us before, which is also one of the few professors at Princeton University who is engaged in cell biology research, but Professor Copperfield is more engaged in the signaling pathway of Navel's research, whether it is my DNA synthase research or Green's cell culture method, I am worried that we will not be well taken care of there, so I came to ask for your opinion, after all, according to the laboratory management rules of Princeton University, You are now our direct leader, and if you were a professor, we would be your student naturally! ”

"May I understand that you don't really want to go to Professor Copperfield?" Junxin asked.

Shirley nodded and said, "That's true!" Let me be clear, Professor Copperfield doesn't have what I need, including resources and room for expansion! ”

Junxin touched his chin, unimpressed by Shirley Xavier's words, he could see that the Princeton Ph.D. graduate student had his own ideas, but needed his own support. After thinking about it, Junxin still said: "If you want to stay, I can only provide you with funds for half a year, you know, I will return to China after half a year, if you can send a big article in half a year, I support your opinion!" ”

"But from my personal point of view, I take over the lab for a maximum of half a year, and generally speaking, the lab will be taken over by other professors, and if you can't complete your own project within half a year, then the next professor may not consider your views after half a year. So I hope you can carefully consider what I say, whether to integrate into Professor Copperfield's experimental team as soon as possible, or to stay in my team, complete my experimental requirements in one fell swoop, and publish a big article. This is important for your future. ”

"Sir, I don't think I need to think about it!" Shirley was completely unmoved, Junxin could see that this girl was definitely a strong-willed person, "I have thought a lot about it since Professor Ivanov left, and I think that if I race against time, there will be no problem in completing my laboratory within half a year!" ”

"Are you convinced?" Jun Xin glanced at her deeply and asked in a serious tone.

"Convinced!" Shirley also replied seriously, and after finishing speaking, she suddenly smiled and said mischievously, "Actually, I saw hope in you, sir!" I would also like to thank you for making my mind stronger! ”

"In that case, the funds will be received within five days, prepare your experiment, and those who don't leave a way back for themselves can only move forward! But I'm optimistic about you! Junxin nodded and said.

"Thank you, sir!"