Chapter 123: Imitation
According to the requirements of the headquarters, Tian Hemeng proposed a 1 billion procurement plan.
Among them, the quota of imported drugs is 500 million yuan, and the purchase quota of the production line is 500 million yuan, and it is promised that when drugs need to be purchased from outside in the future, priority will be given to purchasing from CP Company.
Xie Bin looked at the list of imported drugs in his hand, and his eyes were about to go out.
The above lists [Entecavir Dispersible Tablets], [Magnesium Isolehydryrizate Injection], [Diammonium Glycyrrhizinate Enteric-Coated Capsules], [Entecavir Maleate Tablets], [Erbesartan Hydrochlorothiazide Tablets], [Suvastatin Calcium Tablets], [Alprostadil Injection]...... A total of 44 drugs were required for imports.
Some of these medicines are needed at Aoba Pharmacy and some are needed at Aoba Hospital.
However, Xie Bin has no authority to decide on the introduction of production lines, but he estimates that the headquarters will not refuse, after all, if Zhengda Company does not sell, other companies will also sell.
There are many production lines required by Aoba Medical, mainly focusing on three aspects: cardiovascular and cerebrovascular, anti-tumor, orthopedics, analgesia, and supplementation.
As for the drugs for liver disease, respiratory system, and digestive system, they are not on the list, mainly these drugs, which will be developed by Aoba Medical itself in the future, and there is no need for a Chia Tai production line.
A total of 13 drug lines were selected.
After communication between Xie Bin and the headquarters, the two sides quickly reached an agreement that CP Pharmaceutical would package and sell a batch of drug production lines that were ready to be eliminated or had been eliminated to Qingye Medical.
After the signing of the contract, CP's reserves in Aoba Bank rose to more than 500 million.
However, CP has no idea of withdrawing money, after all, this money will definitely be spent, and with the spread of the effect of the zero disease, and the fact that many regions have not approved the marketing of the zero disease, this means that for a period of time, Honsavady, Siam, and Luzon will become the main channels for AIDS patients around the world to obtain drugs.
……
If it is said that the special drug for AIDS - Ai Qingling, it just makes some intentions around the world.
Then rabid dog nemesis has become a necessity in many underdeveloped regions.
After all, these underdeveloped areas do not have the conditions to popularize rabies vaccine, whether it is for people or pets, there is not enough coverage.
For example, in Siam, there was a large-scale outbreak of rabies in Siam in 18 years.
Many people who have been scratched and bitten by cats and dogs generally do not have enough awareness of prevention, or feel that the price of rabies vaccine is too high, and they have not been vaccinated in time, and then when they get sick, there is basically no cure.
Although the price of rabies nemesis is very high, its characteristics that are still effective in the onset period make its importance skyrocket.
Of course, Tian Hemeng knows that at the current price, there are only a few people willing to buy Rabies Buster.
Therefore, the production capacity of the Rabies Buster production line is very low, even if the production line is fully open, it can only produce 20,000 boxes a month, not to mention that it is now only working for an average of 3 hours a day, and the monthly production volume is only 2,000 boxes.
The production volume is low, and the demand is not high, so the selling price is naturally high.
This kind of niche medicine, Aoba Medical is concentrated in a small town near Taunggyi for co-production.
Usually one drug is produced normally for a week, and then the employee is transferred to the next production hall to produce another drug, and the cycle repeats.
With this kind of production plan, it is also a last resort.
After all, this is the fate of niche drugs, the market is so big, it is too difficult to maintain a production line at full capacity.
Otherwise, Qingye Medical would not have carried out limited sales of Ai Qingling, but it was worried that the market would be saturated and the production line would be scrapped directly.
This is also the reason why many big pharmaceutical companies do not like to develop curative drugs.
It's all about profit.
……
Also for the sake of profit.
Tianzhu's hundreds of generic drug companies have also been moved recently.
A large generic drug company in Mumbai has procured some Ai Qingling through the Tianzhu people in Yangon.
In the lab, the boss Ali asked, "Dr. Kaisha, how is the research going?" ”
Dr. Kaisha, who was wearing a white coat, shook his head: "Mr. Chairman, I'm very sorry, I'm afraid we can't imitate this medicine." ”
"Why?" Ali asked unwillingly: "Could it be that our equipment is not good?" ”
"Mr. Chairman, it's not a problem with the equipment, it's that we don't have raw materials." Dr. Kaisha spread his hands.
Ali frowned: "Raw materials? ”
"Yes, it's the raw material, and this new drug needs to use specialized bacteria, similar to penicillin, streptomycin, and the like."
"Then let's go buy the strain!"
The corners of Dr. Kaisha's mouth twitched slightly: "Hehe, the key is that Aoba Medical has not announced that it uses that kind of bacteria as raw materials, and according to my experience, it is definitely not a common medicinal bacteria." ”
"Damn! These greedy vampires are hiding such crucial information. ”
Hehe, Dr. Kaisha secretly complained to himself, you want to imitate someone else's new drug, and blame others for not announcing the technical details, don't be so shameless.
Ali suddenly had a whim: "I heard that antibiotics can be synthesized artificially now, can you experiment with this method of production?" ”
"Uh...... Mr. Chairman, the active ingredients of the other party's new drug are all macromolecular organic substances, and in order to synthesize artificially, we must first figure out which part of the structure of this macromolecule is at work, and this kind of research requires a lot of money and a long time to study......," Dr. Kaisha explained helplessly.
As soon as he heard that it would take a lot of money and a long time, Ali immediately showed a disappointed expression.
A generic drug company like him originally relied on imitating new drugs developed by others, and it was basically impossible to expect them to invest heavily in the development of a drug with an uncertain future.
In fact, not only Tianzhu generic drug companies are secretly researching imitations.
Even major pharmaceutical companies in Europe and the United States are secretly studying how to imitate.
It's just that they all have the same dilemma.
That is, what kind of bacteria did Aoba Medical use to isolate these three new antibiotics, and now European and American pharmaceutical companies have not found similar macromolecules, so they can only study the structure of these macromolecules, hoping to find out some effective anti-virus structures from them, and then learn from them and improve.
So what kind of bacteria did Aoba Medical use?
The answer is genetically recombinant bacteriophages, which have been modified beyond recognition by Li Qingye, and then use these phages to fight against HIV continuously, and select phages that can resist and kill HIV.
In other words, as a strain for the production of new antibiotics, it is not a naturally occurring bacteria, and other laboratories have no way to obtain this genetically recombinant bacteria, and they have no way to imitate it in a short time.
This is just like when penicillin first came out, those high-yielding strains were the core secrets of various pharmaceutical companies and even countries.
Without high-yielding strains, the production cost of common penicillin is comparable to gold.
Now the strains used in Aoba medical treatment do not even exist in nature, and other laboratories can't even extract a small amount, so how to imitate them in the face of this situation?
You must know that this is not an ordinary inorganic chemical drug, but an organic macromolecule, and it is very difficult to synthesize it artificially.
This is also one of the advantages of targeted antibiotics, without strong enough genetic technology, don't think about imitating targeted antibiotics in a short period of time.
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(End of chapter)