Chapter 220: Pfizer's Movements, Vascular Analysis in Fluid Mechanics
Swiss Bio Valley.
The name of the Swiss Bio Valley is very popular in the biomedical world.
It's like the Silicon Valley of the United States and the Optics Valley of China.
Silicon Valley is well-known in its semiconductor chip industry, and Optics Valley is well-known in optical devices.
And the Bio Valley is naturally in biomedicine.
It is home to almost 40% of the world's pharmaceutical industry, including more than 700 life sciences companies and more than 200 academic or public institutions, and tens of thousands of researchers, making it one of the most prosperous biomedical places in the world.
In addition to the headquarters of Novartis and Roche, companies like Pfizer and Johnson & Johnson have important divisions here.
It can be said that the development of biomedicine in Switzerland and Europe is closely related to this bio-valley.
And at the same time, Biovalley, the laboratory of the Pfizer division.
"How's the experiment going?"
Pfizer Vice President, Mike Conn, walked into the lab and said to Skarna Slavie, who was conducting experiments.
"It's going well."
Skarna Slavi laughs, "We are now very close to the fourth generation of thrombolytic drugs. ”
"At least as far as we know, neither Novartis nor Johnson & Johnson have been able to find an ingredient that can stably inhibit the rise of PAI-1."
"And we discovered such an ingredient the day before yesterday, and now we are trying to prepare it in a directional manner."
"As long as we are done, on the 4th generation of thrombolytic drugs, we are considered victorious!"
Conn immediately smiled and praised, "Well done! ”
"When you succeed, the company will definitely give you a celebration party."
"Haha, then it seems that this celebration party must be opened." Slavi laughed.
显然,对于这个新药物的研发,他已经胸有成竹了。
"When I hear your words, then I will put a hundred hearts at ease." Conn nodded in satisfaction.
Slavi, as their chief scientist of Pfizer, since he has such confidence in success, then Conn, as vice president, naturally has enough trust in this.
At least Slavi rarely let them down.
However, after asking this question, Conn said: "In addition, I have come to tell you another news, Li Mu has arrived in Germany, and he has gone to the laboratory where Kingsley Weil is. ”
Hearing the news, Slavi was stunned for a moment, and finally snorted coldly and said: "That Chinese man is really not giving up, he actually believes in that liar." ”
"It's really smart but it's clever and mistaken by cleverness."
He looked disdainful.
But Conn still asked, "Are you sure that Kingsley Weil is really just a liar, after all, he was really a professor at ETH Zurich." ”
"I also investigated, he was really talented back then, he studied at ETH Zurich for both undergraduate and graduate degrees, and also got a doctorate in biology, and he also published several articles in Cell, and I heard that he was not far from being rated as a professor back then."
After determining that the other party is a competitor, Pfizer will naturally investigate the other party clearly.
李牧就不用多说了,哪怕其在数学和物理学上的成果,都和他们辉瑞没有任何关系,甚至还乐见其成,但是其对生物实验的数据分析,这是实打实的受到了整个生物医学界的称赞。
Therefore, this is first of all a fierce rival, and the other Kingsley Will, although he has always been said by Skarna Slavi to be a liar, when Kingsley Ware approached them for Pfizer and wanted to cooperate, it was also Skana Slavi who prevented him.
At that time, although Skarna Slavi was not the chief scientist of Pfizer, he had already made a lot of contributions, so their president agreed to his request, although Kingsley Weil did not ask for much money at that time, and it was only a drop in the bucket for them.
But now, they have to think about the threat that the other side will pose to them.
然而斯卡纳·斯拉维还是摇摇头,十分确定地说道:“就算是教授,也只是个副教授而已,就更不用说他现在只是个骗子,不值一提。 ”
Seeing Skarna Slavi say this, Mike Conn looked at him deeply, and then said, "Okay, you are our chief scientist, I believe you, but I also hope that you don't affect the company because of your emotions." ”
"Presidents aren't good-tempered, you know. ”
The contradiction between Skarna Slavy and Kingsley Weil was naturally investigated, so it is almost certain that Skarna Slavi was so disgusted with Kingsley Weil because of the contradiction back then.
And that contradiction is still very deep, basically it can't be persuaded.
Hearing Conn's words, Skarna Slavi didn't say anything, but said, "It's time for me to continue experimenting." ”
Conn shook his head suddenly, obviously, Slavi didn't want to hear these words, and began to chase people.
In the company, in terms of status, Slavie's status is still higher than that of his vice president, so he didn't say anything more and left the laboratory directly.
Slavi didn't look back, but remembered Kingsley Weil in his mind, and finally snorted coldly, and then shouted to the other researchers in the lab, "We don't have to think about rest for the next period of time, we have to do our best to achieve our goal!" ”
Suddenly, the personnel in the laboratory were crying, but there was no way, Slavi was the chief scientist, and he was the big leader of their people, so he could only listen.
In this way, their originally relaxed experimental arrangements immediately became intensive.
"Kingsley Weir, I'm not afraid of you, I'm just worried about that Li Mu."
Slavi said in his heart.
……
Time passed quietly.
Outside Oxford University, Li Mu spent a pound to buy the house.
After a few days on the German side, he returned without staying long.
The experiments here have made impressive progress, and they have rediscovered two unknown ingredients, and it is almost certain that this is one of the ingredients that plays the most critical role.
The next task is to determine the specific composition of the ingredient and find out how it works.
It's going to take a bit of work, but for Kingsley Weil, they're excited to make that kind of progress.
As long as they determine the principle of this ingredient and how it is synthesized, and then confirm its efficacy on the human body, as well as possible side effects, etc., they can start preparing for clinical trials.
And these things don't need Li Mu to care about.
He also has to take care of his own affairs......
Of course, strictly speaking, it is not unrelated to this study.
When watching Kingsley Weir and them conduct in vitro thrombolysis experiments, Li Mu had an idea when he watched the simulated blood flow pass through the simulated blood vessels.
Can the analysis of fluid mechanics directly analyze the thrombosis in the blood vessels of the human body?
Of course, it's not just blood clots, but also many possible problems.
For example, atherosclerosis, blood viscosity and so on.
这些问题,都是可以直接利用流体力学分析出来的。
As long as he can establish a general model of the human bloodline, and then use fluid mechanics to analyze each place, then it may be possible in the end, and it is only necessary to draw blood, determine the viscosity of the blood, and measure blood pressure once, and then analyze the various diseases hidden in the blood vessels of the human body.
And there are too many vascular-related diseases......
"It should be doable."
"However, this requires a more in-depth analysis of fluid mechanics."
Li Mu groped his chin.
As long as there is fluid, it can be analyzed by fluid mechanics, and the same is true for blood vessels.
To a certain extent, the analysis of microtubule fluid mechanics is still very enthusiastic for physicists to discuss.
In addition, in biology, there is also a branch called biophysics.
The use of fluid mechanics to analyze the flow of blood is also a research direction.
However, once it is associated with fluid mechanics, it is not a simple problem, and as the last piece of the puzzle in classical physics, the study of fluid mechanics has always been a hot topic - because it has stumped all past physicists.
The biggest problem left here, and the most famous, is the solution of the Neville-Stokes equation.
Solving the Neville-Stokes equation is a hard-to-do thing that can be done except under certain conditions, such as in the simplest parallel flows, where an exact solution can be obtained.
Generally speaking, both the mathematical and physical communities believe that the exact solution of the Neville-Stokes equation cannot be found.
Therefore, among the famous seven mathematical problems of the millennium, the problem with the Neville Stokes equation requires only the existence and smoothness of its solution, but does not require the solution to be obtained directly.
The existence of solutions is easy to understand, that is, to let people know that there is an exact solution, but scientists can't do it, and smoothness is infinite differentiability.
Proving this problem is of great significance for any practical application problem related to fluid mechanics.
Including the problems that Li Mu is facing now.
"Just kidding......" Li Mu twitched the corners of his mouth: "You can't let me prove this thing." ”
Just kidding, this is a millennial conundrum.
The difficulty is quite high.
But at this moment, the voice of the system rang out.
"Bonus Mission Released—"
[Proof: Existence and smoothness of the solution of the Neville-Stokes equation]
……
Take a leave of absence tomorrow
(End of chapter)