Chapter 225: The Best Space for Studying Fluids: Lee's Space

When Kingsley Weil heard Li Mu's words, he was stunned.

After thinking for a moment, he exclaimed again.

"How can they come up with this kind of efficacy?"

Obviously, in Kingsley Weir's view, the side effect carried by PEFF was deliberately caused by Pfizer.

世界上治标但不治本的药很多,但是治标的同时还能够加剧‘本’的严重性的药,那可就很少了。

This kind of medicine is simply the favorite of all pharmaceutical companies.

So, it's scary about this, Skarna Slavi was able to come up with this drug, and his research and development ability is really a little too perverted, right?

Actually developed a drug with a targeted effect?

Li Mu also guessed the reason why Kingsley Weil was so surprised, he waved his hand and said, "It's not necessarily that they did it on purpose, maybe they didn't expect PEFF to have this effect at all." ”

No matter how you think about it, with the current research methods of human beings, it is still very difficult to develop a drug with a directional effect, so it should be that Skana Slavi who inadvertently made it.

他思考了一下,然后就重新进入到了模拟空间中,接着再创造了一堆患有肺栓塞以及急性心肌梗死的患者。

He then injected each of these simulated patients with PEFF, and then began to speed up to observe their physical changes.

After PEFF injection, the blockage of the blood vessels in these patients was more or less relieved, and as the blood flow was restored, pulmonary embolism and acute myocardial infarction were resolved.

However, as time accelerated, Li Mu found that some of the patients showed signs of atherosclerosis in their blood, especially some of the simulated elderly patients, which was the effect of higher platelet activation.

As the accelerated time passed, all of a sudden, Li Mu noticed that one of the elderly patients had a severe cerebral infarction, and then in less than 40 minutes, because he had not received treatment, he went straight to Karma.

Li Mu's eyebrows suddenly raised.

It's kind of interesting.

He only simulated 20 patients here, and one case of this severity occurred.

Moreover, the patients he simulated were all relatively ideal, and the physical problems were relatively simple, and the diseases suffered by the patients in reality were more complicated.

Indefinite cerebral infarction and myocardial infarction can occur together.

Thrombolytic drugs are specifically designed to deal with this type of disease.

After all, compared with interventional therapy, intervention has relatively high requirements for doctors' skills, and the cost of surgery is also very high, while thrombolytic drugs only need to be injected into the body, relying on the circulation mechanism in the body to dissolve thrombolysis, and it is easier for patients to accept.

Therefore, once Pfizer encounters such a problem in the process of clinical trials, and even directly leads to the death of volunteers in clinical trials, it is a huge problem whether their new drug can pass the FDA and EMA review.

FDA and EMA are the drug regulatory agencies of the United States and Europe, and any drug that wants to enter the market in these two regions needs to pass the review of these two organizations, and these two regions are the most developed regions in the world in medicine, and they are also the most developed regions in the pharmaceutical market.

然而想要通过这两个管理组织的审核都非常难,尤其是FDA更是称得上是世界上最严格、最权威的药物监管局。

Generally speaking, as long as the drug has passed the FDA's approval, it is relatively easy to pass the QS certification of Huaguo.

And although Pfizer is famous all over the world, the power behind it is also very large, and there are people in the FDA committee, if PEFF is found to have such a big hidden danger, whether it can pass the review is a question, after all, the FDA also has people from other pharmaceutical companies.

Thinking of this, Li Mu reopened his eyes and looked at Kingsley Weil next to him.

Although he simulated a lot of things just now, in fact, less than a minute had passed.

He already knew the results of PEFF, so now he doesn't care anymore.

"Well, we don't have to worry too much about PEFF."

"Trust our RSCA."

Kingsley Weil came back to his senses, then sighed and said, "Of course I believe in RSCA, this mine is Pfizer after all." ”

The world's largest pharmaceutical company, the absolute giant, is put in awe of everyone in reality.

Li Mu said with a smile: "Don't care too much about this, there is a poem in China, called: He is strong, he is strong, and the breeze blows the hills." He is horizontal, and the bright moon shines on the river. ”

"We just have to do our best."

Hearing Li Mu's words, Kingsley Weil let out a sigh of relief, and then nodded heavily: "You're right, don't care." ”

"Well, that's right."

Li Mu shook his head.

……

For the next period of time, Li Mu continued to stay in Germany, using the simulation function of the brain computer to help Kingsley Weir with their next research.

Just like any drug needs the active ingredient and the auxiliary ingredient to work together, the real cosmic environment simulation, although because the subject has been determined, so it is not possible to study the preparation process and other problems, but he can directly test which ratio of the active ingredient and the auxiliary ingredient has the best comprehensive effect.

For a while, their research speed also became fast, and Kingsley Weir and they were all amazed at how Li Mu did it, and Li Mu often only used one reason to explain, that is, data analysis.

And he often gives the process of data analysis - after all, he already knows the answer, and it is not too simple for him to follow the answer to give the process of data analysis.

So, in this way, Kingsley Weir and they became more and more worshipful of Li Mu as a god, and his data analysis methods were also more and more believed by them, which was the guidance brought by the god of biomedicine.

Of course, while helping them with their analysis, Li Mu did not forget to continue the hydrodynamic analysis of blood vessels.

With the passage of such a long time, he has also sorted out a lot of results.

At present, one of the most outstanding results is that after measuring blood pressure and blood viscosity, it can directly determine whether there is a place where the blood in the human body is not smooth, and can directly determine the part of the human body where the place is not smooth, with an accuracy rate of up to 90%.

This achievement alone is already of great significance, which means that for doctors, when facing a patient who is suspected of having vascular disease, but is not clear where the problem is, they can let the patient first take a blood draw, measure blood pressure, and then calculate which part of the problem may be based on Li Mu's results, so as to directly determine where the problem is and whether it is serious.

In addition to this, Li Mu's results also have a high probability of judging whether there are blood flow problems such as atherosclerosis in the patient's body.

These results, although they cannot help cure diseases, can still save lives, and timely determine what disease the patient is suffering from, of course, is saving lives!

This is the significance of Li Mu's research.

And just like that, the time passed quickly, and it was December.

【Hk={(f,g)|∑|α|≤κ……】

Write the last line at the end of the scratch paper.

Li Mu's brows moved slightly.

"Fluid ...... Fluid ......"

After such a long time of analysis and research on vascular fluid mechanics, his understanding of the entire fluid mechanics has been profound to the point that it is difficult for ordinary people to achieve.

"A fluid is defined as a body of matter that is not resistant to shear stress, and as long as shear stress is applied to a fluid, the fluid is constantly deformed......"

"So the shape of the fluid is always the same as the container, just like the blood in the blood vessels, and obstructions such as thrombosis will cause the shape of the blood fluid to change."

"However, in the current mathematical world, the analysis of different fluids is always different, and the models will be different."

"So is there a fluid analysis method that can describe fluids in all the different situations?"

Li Mu pondered.

The most complicated aspect of fluid research is that there are too many forms of fluids.

The liquid in the pipe is one kind, the fluid in the river is also the other, or the fluid between two flat plates.

Therefore, researchers can often only discuss fluids in different situations.

As a result, there has been no unified analysis method to cover all of these situations.

Therefore, this question made Li Mu have such an idea: "This is very uncomfortable. ”

As a researcher of blood vessels, or pipeline fluids, he has always tried to expand from pipeline fluids to other fluid modes to achieve a unified analysis, but he always fails in this regard.

"That's not right...... Not right......"

Suddenly, Li Mu suddenly came back to his senses, "I have always wanted to make different external environments achieve a unified analysis method, but I haven't thought about how to unify the fluid!" ”

“如果我忽略了外部的剪应力,而仅仅只考虑流体的形状呢?”

"The external shear stress is directly considered as the internal force of the fluid, and the fluid ...... is directly considered as a whole."

The research that has been going on for so long has turned into a sudden realization at this moment.

In an instant, Li Mu found a bright road to the key.

"That's how it should be! Just like the Neville-Stokes equation, which is a unified analysis of all fluids, so if I want to prove the existence and smoothness of its solution, then I first have to find the commonalities that exist in any fluid with different shapes......"

"Differential Geometry...... Smooth manifolds! ”

"Yes, it's like a Richie flow, or some other manifold shape, no matter how the fluid changes, it's just a topological space."

Li Mu's eyes gradually brightened.

"Think of the volume of the fluid as a space, and that's it!"

Almost at the moment when his thoughts were clear, Li Mu picked up the pen and brushed on the scratch paper to write.

Only a moment later, he burst out laughing.

"This is the best space for studying fluids!"

"I'll call it in the future, Li's space is good!"

(End of chapter)