The deciphered viral gene sequences were swiped across the computer screen, with detailed data annotations next to each gene locus, which shows that Dr. Yu's team has not slackened for a moment in the past five years.

"Slow it down. ”

Shen Ke said.

Yuan Zirui glanced at Shen Ke in surprise and adjusted the speed of the picture to twice the speed.

"Hurry up. ”

Yuan Zirui hesitated, and then adjusted the speed to four times.

"Faster. ”

Yuan Zirui and Pan Xueyi looked at Shen Ke at the same time, even if Dr. Yu checked the gene sequence, it would be four times faster at most.

That's because Dr. Yu is familiar with the entire viral gene sequence, so many loci can be skipped.

Shen Ke: What is this for? The first time she watched the strain sequence, she had to be eight times faster? Should she watch cartoons?

"Why don't you adjust it?" Shen Ke looked at Yuan Zirui and Pan Xueyi suspiciously: "This strain sequence should have thousands of pages, right? It's so slow, how long does it take to watch? Hurry up and adjust it quickly." ”

Yuan Zirui had no choice but to adjust the speed to eight times the speed.

At this speed, even if Yuan Zirui deals with virus sequences every day, he can't adapt to it.

"Why is it still so slow? Sixteen times. ”

Yuan Zirui and Pan Xueyi were stunned.

"Miss Shen, are you sure that you can understand such a speed?" Pan Xueyi asked in astonishment.

"I don't understand. ”

Shen Ke said calmly.

"To be honest, even if it's double speed, I can't understand it. ”

“......”

Yuan Zirui and Pan Xueyi both have excellent tempers, but at this moment, how can they want to beat up this stunning beauty around them?

In the end, Shen Ke used sixteen times the speed and only took nineteen minutes to read the entire virus gene sequence.

Later, the virus splitting and replication images were viewed.

A table of changes in the physical sign data of the whole body after the vaccination of volunteers.

Then without saying a word, he left the laboratory.

Yuan Zirui and Pan Xueyi looked at each other.

"Zirui, this Shen Bingyue won't be here to play with us, right?" Pan Xueyi said to Yuan Zirui.

"I think so, too. ”

Yuan Zirui said: "But now in our situation, whether she plays or not, it makes no difference to us, let her want." ”

The two packed up the test equipment and left depressed.

......

After Shen Ke left the laboratory, he immediately went to the commissary, bought some food and drink, and then entered the school library and went straight to the medical floor.

Shen Ke first took out the research books on MERS-CoV, read them all, and had a detailed understanding of MERS.

I read all the books on virology again, and after a day and a night, Shen Ke knew all about the characteristics, prevention and control, and mutation characteristics of various viruses at home and abroad.

However, even so, Shen Ke still did not find a way to determine the MERS-CoV receptor binding domain.

It's no wonder that Dr. Yu has studied viruses all his life, and he can think of all the problems he can think of.

How could he not have imagined that he could inactivate the viral RNase and prevent MERS-CoV from binding to 229E?

Shen Ke had an epiphany skill, and after thinking about it, he might not be able to give himself inspiration just by reading virology books, so he browsed all the existing medical books in the library of Southeast University.

Another day and night passed, and Shen Ke felt that he was already an old expert in medicine.

However, there is still no solution in sight.

"Although the MERS-CoV nucleoprotein is a non-structural protein, its targeting will not change no matter what the active structure is, otherwise the virus will not be able to complete the directional replication work. ”

This is the only possible breakthrough that Shen Ke thought of in the past two days and one night.

But this breakthrough is too reluctant.

Detecting the targeting of non-structural viruses is very difficult, similar to the difficulty of determining the receptor binding domain.

But now there is no other way but this way.

"There's one more night, try it. ”

When Shen Ke walked out of the library, it was already eight o'clock in the evening two days later, and tomorrow morning, people from the Biotechnology Development Center would come to the laboratory.

Shen Ke called Yuan Zirui and Pan Xueyi and asked them to come over to help.

The two didn't say a word, and five minutes later, they met Shen Ke in front of the experimental building.

Even if there is no hope, aspiring young people will do their best.

The three of them entered the laboratory and immediately began to do in vitro serum tests. It mainly mimics viral nucleoprotein replication and tracks viral targets through pigmentase.

As long as the multi-chain decipherment is carried out, the symtropy of thousands of virus monomers is found, and it is considered successful.

Shen Ke did experiments and observed virus activity, Pan Xueyi started, and Yuan Zirui analyzed the virus replication data on the computer.

Once, twice, three times......

From eight o'clock to two o'clock in the evening, the three of them did more than 50 experiments, but they did not find any cotropy in these non-structural proteins.

It's like the highway in Chongqing, completely disorganized.

What is even more desperate is that there is not a single overlap in more than 50 tests and tens of thousands of virus cells.

"Forget it. ”

Pan Xueyi was the first to be unable to support it.

She's not afraid of dark circles under her eyes, and she's not afraid of staying up late to damage her appearance, she's just not confident.

Disheartenedness is more terrible than anything else.

Yuan Zirui didn't say a word, there were still six hours, and the four years of dedication were about to officially end.

His face was as calm as water, but his heart was already full of sorrow.

Not to mention them, Shen Ke became more and more discouraged.

He had long known that there was little hope of success, but he didn't expect it to be so slim.

Dr. Yu's experiment failed, and his own company could officially declare bankruptcy.

"Wait. ”

Yuan Zirui and Pan Xueyi were packing up the test equipment, and Shen Ke suddenly stopped them.

The two stopped and looked at Shen Ke: "Bingyue, what's wrong?"

"Don't speak. ”

Shen Ke motioned for the two of them not to speak, and countless medical terms and virus images flashed in their minds.

MERS-CoV is a non-structural virus, and there is no way to determine the receptor-binding domain.

229E is a highly variable coronavirus, and replication targeting cannot be determined.

The targeting of non-structural viruses does not change with changes in structural activity and mutation.

That is, no matter how difficult it is to determine the targeting of MERS-CoV, it will always be there and will never change.

It's like looking for a needle in a haystack, although the sea is big, the needle is small, and the currents and waves change the appearance of the sea, but the needle is still there.

From start to finish, this fact will not change.

"Yuan Zirui, is the Middle East respiratory syndrome coronavirus derived from the dromedary virus stock solution?" Shen Ke immediately asked.

"Yes, what's wrong?" Yuan Zirui didn't know what Shen Ke meant.

"The structure of the virus protein changes and mutates, but the targeting remains the same, isn't it? If we determine the viral targeting of the dromedary camel virus stock, will we determine the targeting of MERS-CoV?"

"Theoretically, this is the case, but isn't the virus stock solution of dromedary camel MERS-CoV? Yuan Zirui didn't understand what Shen Ke meant at all.