Wu Youxing (1582-1652), the character is also Ke, Han nationality, a native of Dongshan, Wu County. Infectious disease scientist in the late Ming and early Qing dynasties. In 1642, the 15th year of Chongzhen of the Ming Dynasty, the plague was rampant across the country, and nine out of ten households died. The epidemic in Zhili, Shandong, Zhejiang and other places in the north and south was prosperous in May and June, "more than 100 families in one lane, none of them are exempt, dozens of people in one door, and none of them are the only survivors". Doctors treated typhoid fever with no effect. Wu Youke personally experienced each epidemic, accumulated a wealth of information, deduced the source of the disease, devoted himself to research, and wrote a new book "Treatise on Warm Epidemics" based on the results of treatment, which opened a precedent for infectious disease research in China. With his lifelong experience and experience in epidemic treatment, he boldly put forward the theory of "furious gas" causing diseases, which is also a great innovation in the history of medical infectious diseases in the world, so it has won wide respect from future generations.

The era of Wu's life coincided with wars and famine epidemics at the end of the Ming Dynasty, which led to epidemics. According to historical records, in the fourteenth year of Chongzhen at the end of the Ming Dynasty (1641 AD), the temperature epidemic in Shandong, Henan, Hebei, Zhejiang and other places was very popular, and there were many patients, even extending to the whole family. At that time, doctors used the general methods of treating external diseases, or the treatment of typhoid fever, or vainly using the medicine to attack and dispel evil spirits, which were often ineffective, and even led to the prolongation of the disease, further developing to the critical stage, resulting in countless unsuccessful deaths.

In view of the above situation, Wu Youxing devoted himself to research, conscientiously summed up, and put forward a new set of understandings, emphasizing that this disease is a warm epidemic, not wind, not cold, neither heat nor dampness, and not the invasion of the evil of the six prostitutions, but because there is a strange qi between heaven and earth, which is completely different from typhoid fever. It is different from the etiology, pathogenesis, diagnosis and treatment, which separates it from typhoid fever and contributes to the formation and development of the theory of warm disease. Authors.

At the end of the Ming Dynasty and the beginning of the Qing Dynasty, Wu lived in a period of continuous military disasters, famine for many years, and plague raged, and it is reported that there were more than 30 plague epidemics in the country during this period. At that time, the medical profession "adhered to the ancient law and did not conform to the current disease" and "simplified the ancient book with the present disease", so that the ineffective dosage of the drug strongly promoted his thinking, and a strong sense of social responsibility made him determined to explore the temperature disease. "Shi Shi mistakenly ruled the law with typhoid fever, and did not taste its immortality", there are those who died due to failure to treat, and there are those who died due to vain use of compensation and disorderly attack. Through a large number of practices of personally observing and diagnosing diseases and administering medicines, on the basis of inheriting the expositions of his predecessors on warm diseases, he creatively put forward the systematic view that warm disease is different from typhoid fever, and compiled the "Treatise on Warm Epidemics" in 1642, which played a fundamental role in the establishment of the theory of warm disease.