There is definitely a possibility of genetic disease. But the question is, what genetic diseases can meet this set of conditions?

Qian Hongjun was silent for a while, "This ...... It's hard to say. The most similar is of course NMO, Leber is a bit like, but Behcet's disease can also make up for it......"

Genetic diseases are a huge reservoir of diseases, and to this day, people are still able to discover a variety of new types of genetic diseases. There are many other ways that can affect the central Bible and the optic nerve. From various key protein or enzyme deficiencies to genetic immune diseases, these can almost all cause the same symptoms as Tang Min now.

Sun Lien didn't think that he could figure out the problem after a consultation with Qian Hongjun. He just wrote down Qian Hongjun's opinion, and then continued to ask, "If it's some kind of genetic disease that has never been discovered...... How can we be sure it exists?"

"You'll have a lot of work. Qian Hongjun didn't laugh at Sun Lien, who was a little self-conscious. In fact, he really felt that it was not abrupt for Sun Lien to ask this kind of question now—with the level of this kid's black face, it was not completely impossible to really encounter some kind of disease that had never been discovered. "First of all, you have to figure out what the causative factors of this disease are, that is, you have to find its mechanism of action first. Second, through the analysis of the mechanism of action, you can figure out which part of the patient's internal environment is wrong - whether it is a lack of channels in the cell, or a deficiency of some specific protein or enzyme, and then reverse the location of the gene defect according to the current known gene sequence research......"

Sun Lien listened very carefully, and kept taking notes. Qian Hongjun looked at Sun Lien with some curiosity, and then said, "At this rate, it is not impossible to go on for three or five months as fast as three, two or even three or five years as slow...... You'll be able to determine if the disease is a newly discovered genetic disease. ”

"So long?" Sun Lien was startled, he originally thought that this process might only take a month or two. "Can't it be any faster?"

"You have to figure out the causative factors first. Qian Hongjun really felt that Sun Lien was a little overwhelmed this time. "You have to take the right sample and analyze it in sufficient detail. That's a matter of luck...... Anyway, I haven't heard of it once. This is a labor-intensive research process, and no one can save time. ”

Research is hard work, especially when it comes to cases like this one that is uncertain. Repeated sampling and analysis back and forth is a basic operation, and there are not a few people who are stuck for three or five years in this process or even give up.

Sun Lien is really a little numb now. Three or five months as fast, or one or two or even three or five years as slow? He had time to spend on this kind of thing, but Tang Min ...... She may not have to wait that long.

"My advice is to rule out other diseases first, such as autoimmune diseases and tumors. Qian Hongjun put on the steam mask again, "After making sure that these diseases are ruled out, we will consider the genetic problem - this is a little more operable." If you want to deal with genetic problems first...... It's not impossible. Speaking of this, Qian Hongjun seemed to remember something, he ripped off the steam blindfold on his face, and then sat up suddenly, "You can take samples first, and then send them for gene sequencing!"

"Is this okay? Whole gene sequencing is quite expensive, right?" Sun Lien asked with a frown, "Do you have to take another biopsy for sequencing?"

"Biopsies are fine, and peripheral blood should be fine. Whole-genome sequencing anyway. Qian Hongjun seemed quite satisfied with his idea, "The price of this thing is cheaper than mNGS, and the speed is quite fast...... I remember that it would take about two weeks to get a report. If you take a sample...... You can call the company that does the genetic testing and ask them for the testing standard. ”

That's a very good idea. Sun Lien nodded? Stand up and say? "Thank you, Director Qian, this has really helped me a lot. ”

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Empty office? Doctors from both treatment groups were all sent out to arrange and accompany various examinations. Professor Zhang Zhifu has a remote meeting to attend in the afternoon? So he's not in the office either.

Sun Lien sneaked into the office like a thief, and then opened the old thing operation interface on his computer disguised as a desktop pet. And then by spending a full hour? Only then did all the previous diagnostic data be entered into the old thing's computing system.

This time the old thing seems to have encountered a hard bone as well, and he is pacing back and forth at the table? Take a look at the corner with a magnifying glass? After a while, he turned his head and flipped through a thick book on the table about the same height as him, or he squatted on the ground with his head in distress and drew circles, and even a lot of black smoke came out of his head—he looked overwhelmed.

From the operation interface of the old thing, Sun Lien was surprised to find that the computing power occupancy rate of the computing center has risen to 80%? And it's still rising. He scratched his head in surprise? I am still wondering why such a large computing center will occupy so many computing resources because of the estimation of a single case.

However, Sun Lien is not a person who likes to think about these things, and seeing that there are still three hours left in the estimated time for the calculation to be completed, he decided to take this opportunity to contact the gene sequencing company first.

Gene sequencing companies like this kind of place? Sun Lien is not very familiar with it, but the research institute in the school has more dealings with there. Sun Lien is too lazy to flip through the web pages one by one? He made a direct phone call to his roommate, Dr. Cao Xin's junior brother Shen Xi.

"Brother Sun? What are the instructions?" Shen Xi answered the phone and asked very heartily? "Come back late tonight? You want me to leave you a door?"

"I guess I won't be able to go back today? So he needs to be rescued by the Shen family's brother. Sun Lien pretended to be posturing, and then said his true purpose, "Do you have the contact information of a more reliable and accurate gene sequencing company? I have a patient here, and I may want to do a whole genome sequencing." ”

"Do it for people?" Even Shen Xi, who was engaged in basic medical research, was a little surprised after hearing this request, after all, they usually mainly do single-point or proteomic testing, and Shen Xi has never done whole genome sequencing. Especially after hearing that Sun Lien was going to test the "patient", he didn't dare to agree casually - this is a human life and must be taken seriously. After thinking for a while, Shen Xi said, "That's it, Brother Sun, I'll contact the company I have worked with before now and ask about the specific situation." Then I'll ask the other brothers and find a company with high test accuracy for you. ”

"Thank you, thank you. Sun Lien naturally couldn't ask for this, in order to make Shen Xi more motivated when he worked, he even gave a reward, "When my business here is over, my brother will invite you to eat and drink!"

"Forget about drinking, my alcohol consumption is worse than Senior Brother Cao. Shen Xi continued to smile heartily on the other end, as if he had completely stepped out of the shadow brought to him by the previous time management master. However, in the next sentence, Shen Xi revealed his true intentions, "Brother, you really plan to thank me, or let my sister-in-law introduce me to a girlfriend?" ”

"Your sister-in-law is a nurse, and if she can introduce you to a nurse, she will also introduce a nurse. Sun Lien was willing to help Shen Xi, but unfortunately, he didn't dare to say that Hu Jia had a suitable single nurse to introduce to him. "Besides, how can there be any gentleness and consideration in being a nurse? I estimate that there is only one in the entire four hospitals, and it is also your sister-in-law. The other little nurses, they can crack and scold for half an hour if they catch you for a small mistake......" Sun Lien sighed, "Anyway, I will invite you to dinner, and if there is a suitable girl, I will introduce you to it." You're giving me a snack about the sequencing company, it might be a matter of life!"