The role of hormones is relative to the immediate action of the nervous system, which relies on the homeostatic regulation of a larger range of networks, such as distant secretion, paracrine autocrine, specific site, effect (network effect due to distribution formation), action between hormones (synergistic antagonism competition allows all network relations), action and secretion have a certain cycle; The regulation of the number of receptors is a consequence of the expression level of the gene

The formation of a network, a certain path, feedback or regulation are all behaviors of the network

Blood is a flowing tissue, a membrane, and the composition of blood is also a network: the production of blood cells

The heart's beating cycle is also a cyclical change at all levels and is the driving force of blood pressure

i=u/r is the law of the whole

The action of sympathetic and parasympathetic nerves on the heart, blood vessels is based on a holistic set of receptors and neurotransmitters: changes in heart rate, smooth muscle relaxation contraction

Edema is essentially an imbalance in osmotic pressure, which is determined by the effective value, i.e., an intrinsic feature of the network (effective filtration pressure = glomerular capillary blood pressure - plasma colloidal osmotic pressure - intracapsular pressure) can be problematic at each link, or even the whole cannot be carried out (filariasis causes obstruction of lymphatic return)

(capillary pressure + interstitial fluid colloidal osmotic pressure) - (plasma colloidal osmotic pressure + interstitial fluid hydrostatic pressure) = effective filtration pressure

>0→ interstitial fluid production (arterial end) < 0→ interstitial fluid reflux (venous end), and the interstitial fluid can flow in the osmotic pressure of the blood vessels

The formation of blood pressure is the result of the interaction of motility and resistance. The interaction between cardiac ejection and peripheral resistance www.biquge.info form systolic blood pressure, and the interaction between the elastic return force of the aortic artery and peripheral resistance forms diastolic blood pressure.

Influencing factors: aortic elasticity, peripheral resistance, ventricular ejection dynamics, adequate blood filling

Multi-level receptors: pulmonary stretch receptors, proprioceptors, carotid body and aortic body receptors, central chemoreceptors, carotid sinus and aortic arch receptors, which play a variety of roles to form a whole dynamic system, the result of the competition of its forces, that is, the effective value is the final eigen.

Physiology is the bridge, the macroscopic observation of all actions, which is essentially a description of the body's network. The distinction between the internal and external environment is an essential feature, and at the same time, the network maintains a dynamic equilibrium due to the existence of relativity: the production of interstitial fluid, the concentration of urine, and the absorption of the intestines

Metabolism is the essence of the network, and the specific expression is a combination of the actions of our different organs

Excitement is the transformation and transmission of information, adaptation is a feedback adjustment, and the intrinsic nature of the network is periodic

Regulation is multi-layered: neurohumoral and immune, autoregulation. Format: Feedback

The form of the signal, the role is multi-layered

Structure, sequence similarity, acting cells and receptor-producing cells, mechanism of action, conditions, etc., all kinds of cytokines are the products of the selective expression of the network, such as cancer and other diseases are the result of the selective expression of the network. The clinical application we hope for is to find its essence (which is also a dynamically changing network, but it is already a dimensionality reduction treatment), and then use certain drugs and therapies (which is also a network, but we hope that its essence can be coupled with the body's essence, so as to restore the original cycle of the body), which relies on the construction of a panoramic view

The meaning of high and low is the overall change of the network, the results of different processing are different, we need to explore the structure of high dimensions, which can replace the change of a sufficient number of times per unit time from a sufficient number of different times. Such as the degree of correlation between specific changes (the relationship between a disease and a certain molecular concentration). Combined with the idea of a collection of images in photosynth software, our biomedical molecular interactions (like the basic units of images) can be reconstructed into a complete network. Every time a picture is taken an observation, and the set of multiple observations establishes a certain connection sequence according to a certain similarity, that is, a certain panorama, which can refer to genome sequencing

The effect of the network is reflected in probability, that is, the Markov model behind the expression of reality, and large-scale observations can find the basis for comparative eigens

The mechanism of each molecule is a network, and through connection (similarity matching), a multi-dimensional network can be constructed, and a certain path can be selected according to the specific expression

The database is based on the base, and different entities can construct connections (such as structure, sequence similarity, acting cells and receptor producing cells, mechanism of action, conditions), and build different levels of networks through the matching of different similarities, which can be adjusted based on real experience

The signal transduction pathway may be an intrinsic

Acting individually and in combination may be able to discern the effects of coupling and their forms, making the experiment a clarion call for victory rather than a declaration of charge. Top talents find their essence through individual wisdom, and the current Internet era can be approached by calculation, and the original upper limit becomes the lower limit, that is, progress

Disease is a network that is a selective expression of a coupled network of phylotomy, immunology, physiology, biochemistry, pathology, cell biology, and so on

Cytokines, cells, tissues, and organs are all a characteristic level that can become drugs (recovery cycles) while using the layers of competition and resistance of the body in a stable state. Of course, perhaps the hierarchical Nash equilibrium will not be able to achieve this state, and we can introduce a new level of competition

The treatment of antibodies is actually a matching network operation that uses the body's immune system

Cancer antigens, the hallmark proteins of cell membranes, act as an intrinsic. Consider the synthesis of multiple antigens, i.e. network effects, multi-layered applications: peptides, proteins, cells, etc.

The orthogonal of the network is the method of solving the comprehensive effect, and different criteria are different results, which is because of the high-dimensional structure of the network

Wave function properties and quantum properties of networks: relativistic wave equations, Feynman path integrals, quadratic quantization methods, foundations of quantum field theory, fundamentals of quantum electromobility, quantum scattering theory

Bioinformatics is a tool for panoramic integration, with sequences at various levels and similarity matching at different granularities

High-throughput data makes it possible to emerge patterns and build networks that interact with each other, and the real network is based on an expression of it

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