Chapter 21: Another New Medicine
"You, what did you say?!"
After listening to John's introduction, Professor Wolfgang's eyes suddenly widened as the size of a bull's eye, and his right hand snatched a bottle of medicine in his hand like snatching Queen Victoria's crown!
"Sulfonamides!"
Not surprised by Professor Wolfgang's reaction, John smiled and said, "Professor Wolfgang, I can responsibly say that their appearance will be a revolution in the medical field!" From today onwards, human beings will no longer be able to passively accept the invasion of bacteria, but can actively fight them and even subdue them......"
"Sizzle......"
After hearing this, Professor Wolfgang immediately gasped!
Sulfanilamide!
Looking at the bottle in front of him, which was almost no different from aspirin, a huge wave was set off in the heart of the professor of internal medicine! Ever since Pasteur and Koch established bacteriology, physicians, especially the top ones, have become more and more interested in this little thing that is invisible to the naked eye. Especially in recent years, while Koch's discovery in the field of Mycobacterium tuberculosis and Yersinia pestis has caused a sensation in the world, more and more people have turned their attention to how to resist the invasion of these small things.
Of course, the results were very disappointing.
There are also many panaceas on the market that can fight bacteria, which attracted the attention of many people at the beginning of the market, but when people really realize their details, they are left with only disappointment and helplessness. Professor Wolfgang didn't expect that John would also come up with a drug that claimed to fight bacteria!
Seeing Professor Wolfgang's astonished look, John was secretly happy.
For the era when bacteria have not yet developed any resistance and are extremely sensitive to various antimicrobial drugs, the emergence of sulfonamides is definitely an earthquake and is destined to cause a sensation in the entire medical community!
This drug has good antimicrobial activity against most gram-positive and negative bacteria. The most susceptible of these are group A streptococcus, Streptococcus pneumoniae, Neisseria meningitidis, Neisseria gonorrhoeae, Yersella pestis and Nocardia spp.; It also has an inhibitory effect on Chlamydia trachomatis, Plasmodium, Pneumocystis carinii and Toxoplasma gondii trophozoites. However, it is not effective against mycoplasma, rickettsia, and spirochetes, and can even promote rickettsial growth.
In other words, sulfonamides are the clarion call for human beings to fight bacteria!
If any other person suddenly came up to Professor Wolfgang and told him that they had invented a drug that could fight bacteria, the professor of internal medicine might have kicked them out immediately, after all, even a big man like Koch could only find bacteria. And not able to defend against them. But what if the person who came was John? Huntelaar, and if this gentleman has done amazing things in the past year, and invented the miracle drug of aspirin, Professor Wolfgang can't help but take these vials seriously!
"Goo-dong!"
After a heavy throbbing in his throat, Professor Wolfgang asked in a dry voice, "Mr. Huntelaar, is this what you call sulfonamides?" I would like to ask, has your company done experiments before? ”
"Of course!"
Hahaha, John said as a matter of course: "I haven't made any real medicine, how dare I take it from you?" This is the actual animal yàn record that we have just completed. You can see that it is Mr. Ehrlich, who has just left you, who is presiding over the real yàn......"
As he spoke, John took out the report written by Ehrlich from his purse, and at the same time his face was slightly embarrassed.
When John poached Ehrlich from Charlotte Hospital a few years ago, Professor Wolfgang complained a lot, after all, it was not easy to find an experienced and excellent physician these days. Ehrlich is also a member of Professor Wolfgang's team, and he is very favored by the professor of internal medicine. Unexpectedly, it was poached by John.
However, Wolfgang, who had already complained before, also saw it and was very unangry about it. Instead, he nodded solemnly and said, "If it is Ehrlich's completed animal reality, then I am relieved...... Mr. Huntelaar, this so-called sulfonamide ......"
"Not one, but three!"
Shaking his finger subconsciously, John patiently explained.
Sulfonamides have never been a drug, but a general term for a class of drugs. After the first appearance of this drug in the 30s of the 20th century. Pharmaceutical companies have invented thousands of sulfonamides in just two decades, but only a few dozen are commonly used to eliminate those that are ineffective or too toxic.
Sulfonamide drugs can be basically divided into three categories in terms of function.
One is sulfonamides, which are used for systemic infections and are easily absorbed by the intestine. John took out sulfadiazine; One is that the intestine is difficult to absorb, mainly used for intestinal infections, John took out sulfasalazine; Another category is a topical drug, and John took out silver sulfadiazine.
All three are among the most typical sulfonamides in John's memory.
In addition to these three sulfonamides, after John gave their common characteristics and predicted that there were countless similar drugs waiting to be discovered by humans, Mr. Ehrlich did not hesitate to devote himself to the discovery of them after completing the animal reality.
An annual investment of 100,000 marks can ensure that Heinz Pharmaceuticals will have at least twenty sulfonamides in the next five years.
After explaining to the professor of internal medicine the differences between the three drugs and their respective adaptations, Wolfgang's face was already at a loss.
At the end of the 19th century, pharmacology was still in its infancy, and even as a professor of internal medicine at the University of Berlin, he did not know much about drugs. This is still the concept that John didn't dare to mention the half-life of drugs, otherwise Wolfgang would not have treated him like a monster......
"Professor, try it first, just like aspirin."
After explaining clearly, John said with a smile: "Within three months, we will provide you with a hundred bottles of the three sulfonamides, and all you need to do is to keep the numbers and information according to the table we designed, and everyone will take what they need, how about it?" ”
"Of course no problem!"
Without any hesitation, Professor Wolfgang immediately agreed.
After the cooperation of aspirin, he is now quite confident in the drug invented by John, not to mention that after listening to the description of the other party, no doctor in this era can refuse the appearance of sulfonamides!
But......
After a moment of silence, Professor Wolfgang suddenly asked, "Mr. Huntelaar, I would like to ask what will be the price of these sulfonamides if they are officially launched in the future?" ”
"This ......"
It seemed a little surprised that Professor Wolfgang asked this question, but after thinking about it for only two or three seconds, John smiled and said, "For the time being, we haven't set the price for them, but if nothing else, I think it should be at least twice as much as aspirin......" (To be continued......