Although Deputy Director Wang tried his best to avoid intersecting with Fang Hanmin, he was not too stingy when he met Fang Hanmin's warm invitation, after all, he came here to understand the test situation of the new process, and Fang Hanmin was the commander-in-chief of the process transformation, if he categorically rejected Fang Hanmin's kindness, not only would it seem too stingy, but also lose his identity.

Despite this, Lao Wang also wanted to shorten the time he spent alone with Fang Hanmin as much as possible, and he told Fang Hanmin that because time did not allow, he only wanted to go to a few important posts to see.

Fang Hanmin took Lao Wang to inspect the condensation, refining and crystallization posts of the three production units, and introduced him to the difference between the old and new processes and the characteristics of the new process.

Leaving the crystallization post of the fifth production unit, Lao Wang said: "I still have something to do, and I will learn more about it later." And he hurried away.

Looking at the back of Lao Wang's departure, Fang Hanmin shook his head, things gather people in groups, this is not false at all, it seems that it is not easy to release the suspicion with Lao Wang!

Fang Hanmin was just about to turn around and inspect various posts, when he saw Chief Engineer Lao Xia walking into the door of the workshop, he greeted the other party from afar, "Mr. Xia, why are you here?" ”

"I heard that the new process of the first workshop was successfully put into production, so I came to take a look and learn about the production situation by the way."

"Okay, welcome to Mr. Xia's inspection work! I'm going to inspect various posts, let me accompany you to inspect, right? ”

"Do you have time? If you have time, you can take a look with me. ”

"Let's go, if you have time, you should accompany the leader to inspect the work."

"After all, you are the commander-in-chief, with you in front of you, I can ask you at any time if I don't understand."

"Mr. Xia, do you want to take a look at every post, or choose an important post to inspect?" Fang Hanmin also asked.

"How long does it take to read it from start to finish?"

"If you look at it casually, you can see it before you get off work. Look carefully, half a day is not enough. ”

"Oh, let's take a selective look then."

Fang Hanmin took Lao Xia around more than ten positions, unlike Lao Wang, every time he arrived at a post, Lao Xia not only listened carefully to Fang Hanmin's introduction, but also took the initiative to ask some questions of interest.

In the condensation position, Lao Xia analyzed and compared the time and temperature of the new and old processes, "although there is not much difference between the two, the by-product acid gas is gone, which plays a key role in eliminating pollution." ”

"Because the new process adopts a different process route and replaces two raw materials, the pollution of acid gas to equipment and the environment is completely eliminated. In addition, the use of this new condensation reactor not only makes the reaction process easy to control, eliminates the risk factors of the old process, but also improves the selectivity and yield to varying degrees. Fang Hanmin explained.

"Oh, how much better are these two metrics compared to the old process?" Lao Xia seemed to be more interested in this.

"The selectivity is 10 percent higher and the yield is 6 percent higher."

"This is a great benefit to reduce production costs, and the new process is really effective!" Lao Xia said sincerely.

"Isn't this the purpose of process transformation, but also the result of technological progress." Fang Hanmin's words carried a kind of confidence.

When he came to the product refining post, the workers were busy, and Fang Hanmin introduced the specific operation process to Lao Xia, "Because the conversion rate of raw materials has been improved, the new process has shortened the time by one-third in the product refining stage." ”

"That means a 30 percent increase in productivity, right?" Although the specific content of the new process is not clear, the chief engineer Lao Xia is still quite familiar with the general technical process.

"Yes, under the premise of ensuring selectivity, the conversion rate of raw materials is improved, which not only shortens the product refining time, but also improves production efficiency and equipment utilization."

"So, the sulfonamide drug in the first workshop can also expand the production?"

"With this level of production efficiency and the scale of the existing equipment, the output of a workshop can be increased by at least 20 percent at full capacity. But Mr. Xia, you also know that the market for sulfonamides is so big, according to the development trend, this kind of drugs have little potential to tap in the future, and under the squeeze of new drugs with better efficacy and less toxic side effects, its market space will become smaller and smaller. So, equipment capacity is one thing, product market is another. ”

Fang Hanmin said it more tactfully, but the meaning is very clear, that is, the output should be determined according to the market, and the market for sulfonamides will gradually shrink, even if the equipment capacity allows, the output cannot be blindly expanded.

On this issue, Lao Xia didn't seem to agree with Fang Hanmin's point of view, "Are you saying that sulfonamides are about to become obsolete?" Is it your imagination, or is there any proof of it? ”

"At the National Pharmaceutical Science and Technology Symposium in May, experts were almost unanimous in their optimism about the future of sulfonamides, not that such drugs would soon become obsolete, but that its clinical application prospects were not very bright, because the high-efficiency and low-toxicity drugs to replace it were being developed and progressing smoothly, and they would be used in the clinic within about three to five years."

In fact, this is entirely Fang Hanmin's own opinion, because at the National Pharmaceutical Science and Technology Symposium in May, no expert mentioned the future of sulfonamides. However, the traverser, a doctor of pharmaceutical science from the University of Oxford in the 21st century, knows that sulfonamide antimicrobials, which have high toxicity and side effects, will be replaced by other antimicrobial drugs with high efficiency and low toxicity in a few years.

Although Lao Xia is the chief engineer of the Red Star Pharmaceutical Factory, the position of chief engineer of a local state-owned enterprise of this scale has actually become an administrative position, because he neither pays attention to new technologies and new products, but also hardly conducts technical exchanges with the outside world, let alone engages in technology research and development.

Fang Hanmin knew that his point of view could not convince Lao Xia, he moved out the expert opinions at the National Pharmaceutical Science and Technology Symposium in May, Lao Xia has always been more superstitious and authoritative, when he heard that the experts thought so, he actually believed it a little, "Sulfonamides are outdated, what should Hongxing Pharmaceutical Factory do?" ”

"Mr. Xia, the outdated statement is not accurate, I would rather describe this matter with the gradual shrinking of the market space. This includes three implications: first, as I said just now, antimicrobial drugs to replace sulfonamides are still under development, and there are at least three to five years before clinical application; Second, even if the products that replace sulfonamide antimicrobial drugs are used in clinical practice, it is impossible to completely replace them overnight, and there must be a gradual process. Third, although sulfonamide antimicrobial drugs have shown many shortcomings in clinical application, they are still inseparable from them in some special fields. ”

Lao Xia nodded, "In other words, this medicine will not be discontinued all at once." ”

"It is unlikely that production will be stopped for the foreseeable future. What I want to explain is that because its market space is getting smaller and smaller, even if the production capacity of the equipment in the first workshop is fine, there is no need for the Red Star Pharmaceutical Factory to expand its output. ”

Because it led to additional topics, Fang Hanmin and Lao Xia stayed in the product refining position for more than half an hour, "Mr. Xia, do you want to take a look elsewhere?" ”

Lao Xia looked at his watch, "There is still an hour before I get off work, and then I will go to other posts." ”

The two came to the crystallization post, and Fang Hanmin introduced the process conditions and operation process to Lao Xia as usual, "The role of this post in the new and old processes is almost the same, but the size of the crystalline particles is different. ”

"Oh, does it have any effect on the quality of the product?" Lao Xia immediately became alert.

"It has been tested several times and there is no impact on the quality of the product."

"Have you done any analysis, what causes the size of the crystalline particles to change?"

"Obviously, because the raw material routes are different, the condensation reaction mechanism changes, which affects the crystallization rate, and ultimately leads to a difference in the size of the crystal particles."

"As long as there is no change in the purity of the product, the size of the crystal particles is not a problem, because the user has to crush it during use."

"In fact, because the crystal particles obtained by the new process are smaller, the impurities entrained in the crystals are relatively few, and the content of the product has been slightly improved through multiple tests and comparisons."

"Well, it makes sense, the larger the crystal particles, the more likely they are to carry impurities."

......

Three days later, Fang Hanmin came to Director Yuan's office and reported to him on the process transformation of a workshop. ”

"There is no rush in the written materials, you can roughly talk about the process, and then talk about the results in detail." Director Yuan always understood this young man very well.

After listening to Fang Hanmin's report, Lao Yuan was very satisfied with the results, "The process transformation is very successful, this is the role of technological progress, so Hongxing Pharmaceutical Factory must unswervingly implement the previously formulated plan for scientific and technological progress." ”

"Now that the work of the technical section in the first workshop has been completed, it stands to reason that our people should be withdrawn, but ......"

"The work you are responsible for is completed, of course, the people in the technical department should be withdrawn, otherwise, the leaders of the first workshop will not be able to work. What, is there any problem? Seeing that Fang Hanmin didn't finish his words, Lao Yuan asked.

"I'm worried about whether the two leaders of the first workshop can effectively manage production after the people from the technical department are evacuated." Fang Hanmin whispered.

"At the beginning, the two leaders of the second workshop can take over the management after you leave, why can't the first workshop?"

"Director Yuan, the specific situation is different! When they were engaged in process transformation in the second workshop, their workshop directors and technicians followed closely throughout the process, and finally they were very familiar with the operation essentials and precautions of each position. The two leaders of the first workshop, especially their director Su, sat in the office every day, basically ignoring the situation in the workshop, and I felt that he did not fully understand the new process. ”

"I see! Are you worried that Lao Su has not mastered the new technology, and that he will make a mistake in management? ”

Fang Hanmin nodded and did not speak.

"But this is just your worry, if Lao Su is studying in secret and deliberately does not let you know, in fact, people already know the new process well, is it possible?" Lao Yuan is the director of the factory, and he has rich experience, and he is more cautious than Fang Hanmin in considering problems.

Although Fang Hanmin didn't believe that Su Wenquan would learn the new process in secret, he couldn't deny that Director Yuan put forward this hypothesis, after all, his worries were also an unfounded speculation.

"Maybe, Director Su is an old leader in the factory, and he should have enough consciousness." Fang Hanmin said stupidly.

A day later, after explaining some precautions to the two leaders of the first workshop, Fang Hanmin and the two assistants all withdrew to the technical department, and he asked Jiang Guoxin and Xu Hui to sit in the office, ready to prepare a written report on the process transformation of the first workshop.

For this technical transformation, the two assistants have been busy for three or four months, unlike Fang Hanmin, they are all family people, soaked in the construction site for a long time, not only tired themselves, but also rarely take care of their families, so that Fang Hanmin felt a little ashamed of them, and now that they are finally busy, Fang Hanmin wants to give the two assistants a few days off.